Dual Diagnosis

Abstract

Depressive disorders and substance use disorders are the most common dual pathologies in the substance abuse field. It is difficult to establish whether the depressed state is induced or rather independent of substance use and/or abuse, therefore, making the therapeutic approach more complex. This article presents the state of the art of the currently available pharmacologic treatments of comorbid depression in patients with alcohol, cocaine, heroin, and tobacco dependence disorders, thus emphasizing the safety and tolerability of various antidepressant drugs. Finally, it is also aimed to call attention on the appropriate recommendations for the use of antidepressants in patients with this dual pathology.

Guía de práctica clínica para el tratamiento farmacológico y psicológico de los pacientes adultos con depresión y un diagnóstico comórbido de trastorno por uso de sustancias

“…de sustancias, así como un mayor riesgo de conducta suicida (Torrens et al, 2011;Torrens et al, 2012). Además, los profesionales de la salud mental y del tratamiento del TUS se enfrentan a las dificultades de brindar asistencia eficaz a los pacientes cuyos problemas se solapan entre dos especialidades de atención sanitaria.…”

<p>Co-Occurring Psychiatric and Substance Use Disorders: Clinical Survey Among a Rural Cohort of Italian Patients</p>

“…In fact, according to the epidemiological study conducted in 2011 by the Substance Abuse and Mental Health Services Administration, SAMHSA, only 44% of patients with DD was treated for either disorder 3. Just to report some examples of the high prevalence, and high prevalence variability of DD among patients with SUD found by European studies, comorbidity of schizophrenia and SUD prevalence is estimated to be 30–66%,4 comorbidity of depression and SUD prevalence is 12–80%,5 comorbidity of personality disorder and SUD prevalence is 45% 6. Although the absence of a defined epidemiological prevalence rate, the association between MI and SUD is clear.…”