Dual Energy Computed Tomography Scans of the Bowel

Yeh, Benjamin M.; Obmann, Markus M; Westphalen, Antonio C.; Ohliger, Michael A.; Yee, Judy; Sun, Yuxin; Wang, Zhen J.

doi:10.1016/j.rcl.2018.05.002

Cited by 22 publications

(5 citation statements)

References 27 publications

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“…Conventional CT performed for the diagnosis of GI bleeding is dependent on the acquisition of multiple phases: a noncontrast series is obtained to distinguish hyperattenuating ingested material or calcification from extravasated iodinated contrast. Arterial and delayed phases facilitate depiction of extravasated contrast within the bowel lumen, which increases in volume and changes in morphology as subsequent series are obtained [12 ▪ ]. DECT simplifies and streamlines detection of potential active extravasation, as iodine maps generated from the dual-energy technique increase conspicuity of acute contrast extravasation, whereas virtual noncontrast images obviate the need for acquisition of an additional noncontrast phase and thus reduce radiation exposure (Fig.…”

Section: Computed Tomographymentioning

confidence: 99%

“…DECT simplifies and streamlines detection of potential active extravasation, as iodine maps generated from the dual-energy technique increase conspicuity of acute contrast extravasation, whereas virtual noncontrast images obviate the need for acquisition of an additional noncontrast phase and thus reduce radiation exposure (Fig. 1) [12 ▪ ,13,14]. DECT can differentiate small bowel adenocarcinoma and primary small bowel lymphoma through differential iodine content of the masses in the arterial phase [15 ▪ ].…”

Section: Computed Tomographymentioning

confidence: 99%

“…DECT can differentiate small bowel adenocarcinoma and primary small bowel lymphoma through differential iodine content of the masses in the arterial phase [15 ▪ ]. DECT has the potential to delineate tumor histology based on the differences in the iodine density of well-differentiated and poorly differentiated enteric malignancies [12 ▪ ,16,17]. DECT can also assess disease activity in patients with CD.…”

Section: Computed Tomographymentioning

confidence: 99%

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Small bowel radiology

Olson

Navin²,

Welle³

et al. 2021

Current Opinion in Gastroenterology

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Purpose of review Recent advances in computed tomography (CT), ultrasound (US), magnetic resonance imaging (MRI), and nuclear radiology have improved the diagnosis and characterization of small bowel pathology. Our purpose is to highlight the current status and recent advances in multimodality noninvasive imaging of the small bowel. Recent findings CT and MR enterography are established techniques for small bowel evaluation. Dual-energy CT is a novel technique that has shown promise for the mesenteric ischemia and small bowel bleeding. Advanced US techniques and MRI sequences are being investigated to improve assessment of bowel inflammation, treatment response assessment, motility, and mural fibrosis. Novel radiotracers and scanner technologies have made molecular imaging the new reference standard for small bowel neuroendocrine tumors. Computational image analysis and artificial intelligence (AI) have the potential to augment physician expertise, reduce errors and variability in assessment of the small bowel on imaging. Summary Advances in translational imaging research coupled with progress in imaging technology have led to a wider adoption of cross-sectional imaging for the evaluation and management of small bowel entities. Ongoing developments in image acquisition and postprocessing techniques, molecular imaging and AI have the strongest potential to transform the care and outcomes of patients with small bowel diseases.

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Section: Computed Tomographymentioning

confidence: 99%

Section: Computed Tomographymentioning

confidence: 99%

Section: Computed Tomographymentioning

confidence: 99%

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Small bowel radiology

Olson

Navin²,

Welle³

et al. 2021

Current Opinion in Gastroenterology

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“…Low keV VMI accentuates iodine-enhanced structures at an acceptable image noise, decreasing the amount of injected contrast media, improving the image contrast of normal blood supply vessels to clearly distinguish between an inflamed and a normal bowel tissue (18,19).…”

Section: Introductionmentioning

confidence: 99%

Application of multi-spectral CT imaging in Crohn's disease: a systematic review

et al. 2023

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Background No quantitative computed tomography (CT) biomarker is actually sufficiently accurate to assess Crohn’s disease (CD) lesion activity, with adequate precision to guide clinical decisions. Purpose To assess the available literature on the use of iodine concentration (IC), from multi-spectral CT acquisition, as a quantitative parameter able to distinguish healthy from affected bowel and assess CD bowel activity and heterogeneity of activity along the involved segments. Material and Methods A literature search was conducted to identify original research studies published up to February 2022. The inclusion criteria were original research papers (>10 human participants), English language publications, focus on dual-energy CT (DECT) of CD with iodine quantification (IQ) as an outcome measure. The exclusion criteria were animal-only studies, languages other than English, review articles, case reports, correspondence, and study populations <10 patients. Results Nine studies were included in this review; all of which showed a strong correlation between IC measurements and CD activity markers, such as CD activity index (CDAI), endoscopy findings and simple endoscopic score for Crohn's disease (SES-CD), and routine CT enterography (CTE) signs and histopathologic score. Statistically significant differences in IC were reported between affected bowel segments and healthy ones (higher P value was P < 0.001), normal segments and those with active inflammation ( P < 0.0001) as well as between patients with active disease and those in remission ( P < 0.001). Conclusion The mean normalized IC at DECTE could be a reliable tool in assisting radiologists in the diagnosis, classification and grading of CD activity.

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“…In the acute setting, computed tomography (CT) is favoured. Recently Dual-energy CT (DECT) has shown promise in the detection of mesenteric ischaemia and gastrointestinal bleeding as well as in inflammatory bowel disease, with an added advantage of reduced radiation dose [9,10]. DECT also has the ability to offer an added benefit in differentiating tumour subtype based on the differences of iodine density.…”

mentioning

confidence: 99%

Editorial: Traversing through the small bowel and what not to miss

Sidhu

2021

Current Opinion in Gastroenterology

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Dual Energy Computed Tomography Scans of the Bowel

Cited by 22 publications

References 27 publications

Small bowel radiology

Small bowel radiology

Application of multi-spectral CT imaging in Crohn's disease: a systematic review

Editorial: Traversing through the small bowel and what not to miss

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