Dual functional antifouling and bactericidal proteinaceous coating

Protein-based bioactive coatings: from nanoarchitectonics to applications

“…9c). [271][272][273][274][275][276][277] For instance, grafting poly(ethylene glycol) (PEG) onto lysozyme rapidly forms an effective antifouling nanofilm, deterring oral bacteria adhesion. 271 Additionally, grafting polyzwitterions 272,273 onto lysozyme and enhancing bactericidal properties by grafting chitosan onto lysozyme demonstrate the potential of these approaches in surface modification and biomedical applications.…”

“…271–277 For instance, grafting poly(ethylene glycol) (PEG) onto lysozyme rapidly forms an effective antifouling nanofilm, deterring oral bacteria adhesion. 271 Additionally, grafting polyzwitterions 272,273 onto lysozyme and enhancing bactericidal properties by grafting chitosan onto lysozyme demonstrate the potential of these approaches in surface modification and biomedical applications. 278 These developments are advancing the field of surface interface research, offering new tools and strategies for enhancing material properties and biological performance.…”

“…In addition, through the conjugation of amyloid-like proteins with polymers, including the chemical coupling of hydrophilic polymers like PEG 271 and polyzwitterions, 272,273 the antifouling properties of amyloid proteins can be substantially enhanced, resulting in improved protein utilization. The film created using this method is nearly a monolayer nanofilm, characterized by its simplicity, transparency, and bio-friendly nature.…”