Dual-Mechanism Tuned Engineered Polyphenols with Cascade Photocatalytic Self-Fenton Reaction for Sustainable Biocidal Coatings

Abstract

Traditional disposable personal protective equipment (PPE) only blocks pathogenic bacteria by mechanical filtration, with the risk of recontamination and transmission remaining. Herein, inspired by phenolic-enabled nanotechnology (PEN), we proposed engineered polyphenol coatings by plant-derived aromatic aldehydes and metal involvement, denoted as FQM, to obtain the desired photocatalysis-self-Fenton antibacterial performance. Experiments and theoretical analysis proved the dual mechanism of Fe-induced enhancement: (1) tuning of molecular structure realized improved optical properties; (2) Fe­(III)/Fe­(II) triggered photocatalytic cascade self-Fenton reaction. Mechanism study reveals FQM killing bacteria by direct-contact ROS attack and gene regulation. Further, the FQM was developed as the ideal antibacterial coating on different fabrics (cloth cotton, polyester, and N95 mask), killing more than 93% of bacteria after 5 cycles of use. Such photocatalysis-self-Fenton coatings based on engineered polyphenols endowed with desirable safety, sustainability, and efficient antibacterial features are promising solutions to meet the challenges of the currently available PPE.

Clinically Approved Ferric Maltol: A Potent Nanozyme with Added Effect for High-Efficient Catalytic Disinfection

“…The above experimental results show that the main kind of free radical generated by the reaction is O 2 ·– . To further demonstrate the underlying mechanism for the outstanding peroxidase-like activity of FM, the DFT calculations were performed, which were desired to support antimicrobial theory studies. , The detail computational methods are offered in the experimental section. Figure a introduces the differential charge density of H 2 O 2 molecules adsorbed on FM and indicates that H 2 O 2 prefers to adsorb in the vicinity of a FM molecule with an adsorption energy of −2.21 eV .…”

“…to support antimicrobial theory studies. 44,45 The detail computational methods are offered in the experimental section. Figure 3a introduces the differential charge density of H 2 O 2 molecules adsorbed on FM and indicates that H 2 O 2 prefers to adsorb in the vicinity of a FM molecule with an adsorption energy of −2.21 eV.…”

Thermal-Driven Curcumin Release Film with Dual-Mode Synergistic Antibacterial Behavior for Efficient Tangerine Preservation

“…With the improvement in living standards, people’s demand for the variety and quality of fresh fruit is also increasing. However, the fruits are inevitably damaged and spoilt in the process from the production area to the sale place due to the microbial infection, resulting in great economic loss and severe resource waste. , Packaging can effectively inhibit the growth of microorganisms by the properties of antimicrobial, isolating the oxygen and water required by microorganisms, thus extending the shelf life of fruits. − The problems of low antimicrobial ability and excessive consumption of petrochemical resources caused by mainstream plastic packaging have drawn growing concern. To counter these drawbacks, natural polysaccharide packaging films incorporated with natural active substances (essential oils and phenolic/flavonoid compounds, etc.)…”

Dual-Readout Ultrasensitive Lateral Flow Immunosensing of Salmonella typhimurium in Dairy Products by Doping Engineering-Powered Nanoheterostructure with Enhanced Photothermal Performance

“…1−3 Foodborne pathogens are widely polluted, spread swiftly, and do excellent harm, which has a great impact on human health and the economy and has turned out to be a premier public health problem in the world. 4,5 Among them, Salmonella typhimurium (S. typhimurium) is a particularly notorious intestinal pathogen, which is associated with the outbreak of numerous foodborne diseases. 6,7 The incidence rate of S. typhimurium ranks first among Salmonella infections and S. typhimurium can induce nosocomial infection and fulminant food poisoning with a high fatality rate.…”

“…Foodborne gastrointestinal bacterial pathogens are one of the major foodborne pathogenic bacteria causing human diarrheal diseases, such as diarrhea, abdominal cramping, and vomiting. − Foodborne pathogens are widely polluted, spread swiftly, and do excellent harm, which has a great impact on human health and the economy and has turned out to be a premier public health problem in the world. , Among them, Salmonella typhimurium (S. typhimurium) is a particularly notorious intestinal pathogen, which is associated with the outbreak of numerous foodborne diseases. , The incidence rate of S.…”