Ductus venosus studies in fetuses at high risk for chromosomal or heart abnormalities: relationship with nuchal translucency measurement and fetal outcome

Bilardo, C. M.; Müller, M. A.; Zikulnig, L.; Schipper, Maria; Hecher, Kurt

doi:10.1046/j.1469-0705.2001.00387.x

Cited by 139 publications

(131 citation statements)

References 22 publications

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“…As Antolin et al found, if both parameters were combined, the sensitivity decreased to 55% 7 . Furthermore, in our study, the false negative rate was 23%, with 14 fetuses with an abnormal karyotype out of 60 with an abnormal nuchal translucency measurement, but normal ductus venosus flow 6 . The real clinical value of ductus venosus Doppler seems to be the possibility to evaluate the further prognosis in terms of pregnancy outcome if nuchal translucency is increased and the karyotype is normal.…”

Section: In This Issue Ultrasound In Obstetrics and Gynecologymentioning

confidence: 88%

“…Furthermore, there is also a significant correlation between abnormal ductus venosus waveforms and adverse outcome in chromosomally normal fetuses due to multiple congenital anomalies and unexplained intrauterine deaths 6 . There are contradictory results regarding the correlation between nuchal translucency thickness and ductus venosus pulsatility.…”

Section: In This Issue Ultrasound In Obstetrics and Gynecologymentioning

confidence: 99%

“…So, how should waveforms with forward and reversed flow occurring in the same fetus or even synchronously during the same registration period be measured and classified? This problem may lead to the poor interobserver reproducibility of the S/ D ratio 4 and is exemplified by the illustrative images of Doppler signals in this issue 4,6 .…”

mentioning

confidence: 99%

“…Severe placental insufficiency, which may lead to fetal compromise and abnormal flow in the ductus venosus during the second half of pregnancy, does not seem to play a role in the first trimester, as no association between placental resistance and increased nuchal translucency or chromosomal abnormalities has been found 9 . Two reports 6,7 …”

mentioning

confidence: 99%

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Assessment of ductus venosus flow during the first and early second trimesters: what can we expect?

Hecher

2001

Ultrasound in Obstet & Gyne

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Section: In This Issue Ultrasound In Obstetrics and Gynecologymentioning

confidence: 88%

Section: In This Issue Ultrasound In Obstetrics and Gynecologymentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Assessment of ductus venosus flow during the first and early second trimesters: what can we expect?

Hecher

2001

Ultrasound in Obstet & Gyne

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“…Los mejores resultados se obtienen entre la semana 18 y 22 de gestación (17,18), aunque hoy en día los nuevos equipos cuentan con mayor resolución, por lo que el examen se inicia a la semana 11 a la 14, donde se hace correlación con la translucencia nucal (TN) y el ductus venoso, siendo factor de riesgo para DCC tener una TN > percentil 95 o > 3,5 mm (19)(20)(21).…”

Section: Introductionunclassified

Prevalencia de hallazgos anormales en ecocardiogramas fetales en el Hospital Universitario de Santander, Bucaramanga (Colombia), 2007-2013

Peñaloza-Wandurraga¹,

Prada-Motta²,

Otero-Pinto³

2015

Rev. Colomb. Obstet. Ginecol.

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Objetivo: describir la prevalencia de hallazgos anormales en ecocardiogramas fetales y los hallazgos anormales más frecuentemente encontrados. Materiales y métodos: estudio de corte transversal, en pacientes con indicación para realizar ecocardiograma fetal por presencia de factores de riesgo o sospecha de anomalía en el ultrasonido obstétrico, atendidas en la Unidad Materno-Fetal del Hospital Universitario de Santander, Bucaramanga (Colombia), institución de salud de tercer nivel de complejidad, que atiende población perteneciente al aseguramiento subsidiado por el Estado, en el periodo comprendido entre 2007-2013. Se realizó muestreo consecutivo. El examen lo realizó un investigador con un ecógrafo marca MEDISON V10, por medio de la ecocardiografía 2D con Doppler color y Doppler espectral. Se describen la edad gestacional (EG), la fracción de eyección (FE) y las anomalías encontradas, que se clasificaron en cinco subgrupos: anomalías de la unión AV derecha, de la unión AV izquierda, cono truncales, del septum y trastornos de la conducción. Los resultados se presentan mediante estadística descriptiva. Resultados: en el periodo descrito se realizaron 99 ecocardiogramas fetales, 40 de ellos fueron descritos como normales (40,4 %) y 56 fueron categorizados como anormales (59,6 %). Se encontró un total de 130 hallazgos anormales: 33 anomalías septales, (25,3 %), 32 anomalías conotruncales (24,6 %), 27 anomalías de la unión AV derecha (20,7 %), 12 de la unión AV izquierda (9,2 %) y 7 desórdenes de conducción (5,3 %). Conclusiones: la prevalencia de hallazgos anormales en la ecocardiografía fetal en gestantes con indicación de realizar ecocardiograma fue de 59,6 % en nuestra institución. Palabras clave: corazón fetal, cardiopatías congénitas, ecocardiografía, ecocardiografía Doppler. ABSTRACTTo describe the prevalence of abnormal findings in foetal echocardiograms, and the most frequent abnormalities found with this imaging study.

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Using second trimester ultrasound and maternal serum biomarker data to help detect congenital heart defects in pregnancies with positive triple‐marker screening results

Jelliffe‐Pawlowski

Walton-Haynes

Currier

2008

American J of Med Genetics Pt A

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Congenital heart defects (CHDs) are the most common of all birth defects. For many newborns with a CHD, prenatal versus postnatal detection is associated with substantially decreased morbidity and mortality risks. Although technological advances in fetal echocardiography have led to an increased capacity to detect CHDs prenatally, pregnancies without an identified risk factor are not routinely screened. With the aim of identifying pregnancies at increased risk for CHDs, this study examined the relationship between CHDs and typically collected second trimester biomarker data collected on a large population-based sample of singleton pregnancies with one or more second trimester screen positive result for Down syndrome, trisomy 18 (T-18), Smith-Lemli-Opitz syndrome (SLOS), or a neural tube defect (NTD). Where possible, logistic models for cases and controls were built and potential referral models were tested among study subsamples with information on the presence or absence of CHDs reported pre- and perinatally. When considered in combination, screen positive for T-18, screen positive for SLOS, nuchal fold measurement > or = 5 mm, and/or having an adjusted hCG multiple of the median > or = the 95th centile detected 42.7% of all pregnancies with a CHD in the combined subsample (where co-occurrence with chromosomal defects was not considered) and detected 29.7% of all pregnancies with a CHD in the no-chromosomal defect subsample. A nuchal fold measurement > or = 5 mm detected 18.2% of those with a CHD in the Down syndrome subsample and an adjusted hCG multiple of the median (MoM) < or = 5th centile detected 92.9% of those with a CHD in the T-18 subsample.

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Ductus venosus studies in fetuses at high risk for chromosomal or heart abnormalities: relationship with nuchal translucency measurement and fetal outcome

Abstract: ABSTRACT

Cited by 139 publications

References 22 publications

Assessment of ductus venosus flow during the first and early second trimesters: what can we expect?

Assessment of ductus venosus flow during the first and early second trimesters: what can we expect?

Prevalencia de hallazgos anormales en ecocardiogramas fetales en el Hospital Universitario de Santander, Bucaramanga (Colombia), 2007-2013

Using second trimester ultrasound and maternal serum biomarker data to help detect congenital heart defects in pregnancies with positive triple‐marker screening results

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