“…Although duplication cysts can be seen at any level of alimentary tract from mouth to anus, with varying types,shapes and sizes; they mostly appear in distal ileum, followed by the esophagus, colon and jejunum [2,4,5] . They are usually located in the second or the third parts of duodenum, communicating with duodenal lumen in 25% of cases [6,7] . However, any cases of duodenal duplication cysts extending into the posterior mediastinum were not reported in the literature.…”