Duplex color doppler study of uterine artery in early diagnosis of preeclampsia

Abstract

Background: This cross sectional study was carried out to observe Doppler wave form in subjects with preeclampsia enrolling 40 subjects with preeclampsia, in the Department of Radiology and Imaging, Dhaka Medical College Hospital, Dhaka, over a period of six months from 20th May 2012. A total number of 40 normal pregnancies were also included for comparison.
 Methods: Objective of the study was to observe Doppler wave form in subjects with preeclampsia. While specific object is To see PSV, EDV, RI, PI in different groups of study subjects from 24th to 37th weeks and find out significant difference of different Doppler indices in between two groups (i.e.,to calculate the proportion of subjects having early diastolic notch in two groups).
 Results: Majority (35% in normal and 37.5% in preeclampsia) of the respondents were found in the age group of 21-30 years. Unpaired t-test revealed no significant difference between mean age between two groups. Among normal group, mean±SD PSV, EDV, PI and RI were 43.94±15.41 cm/sec and 15.51 (±4.93) cm/sec, 1.12±0.0846 and 0.571 (±0.058) respectively. Mean PSV, EDV, PI and RI were 83.19±18.44 cm/sec, 11.86±5.19 cm/sec, 2.497±0.369 and 0.8255±0.087 in preeclampsia group. There was statistically significant (By unpaired t-test) difference in mean Doppler indices between these two groups. It was observed that early diastolic notch was found in 90% subjects with preeclampsia. Early diastolic notch was observed in Doppler wave form in 5% subject with normal pregnancy. Chi-square test showed that there was statistically significant difference in presence of early diastolic notch between normal subjects and subjects with preeclampsia.
 Conclusion: It may be concluded that doppler indices with presence of early diastolic notch are reliable indicators for early detection of preeclampsia.
 Bangladesh Med Res Counc Bull 2019; 45: 34-40