To highlight the detection of venous thrombosis by doppler sonography in patients clinically suspicious of having vascular lesions in lower limb. MATERIALS AND METHODS: A total of 100 consecutive patients who were clinically suspicious of having vascular diseases of lower limb were subjected to doppler sonography. The study was carried out in the department of Orthopaedics & Radiodiagnosis, J.N. Institute of Medical Sciences, Porompat, Imphal during the period between July, 2009 and December, 2012. RESULTS: The study includes 55 males and 45 females with the age ranging from 18-80years. Sonographic diagnosis was made in 80 patients and no abnormal findings were detected in 20 cases. The most common lesion detected was deep vein thrombosis (DVT) in 34(42.5%) cases. The other lesions detected were 30 (37.5%) cases of atherosclerosis, 15 (18.75) varicose vein, 5(6.35) synovial cysts, 3(3.8%) superficial vein thrombosis (SVT), 2(2.5%) each of aneurysm and arteritis, 1(1.3%) each of arterial occlusive disease, arteriovenous malformation, acute lymph adenitis, calcified cystic lesions and inflammatory lesion. The commonest age group of DVT was between 41-50years and there was male preponderance with male: female (M: F) ratio of 1.26:1. The most commonly involved vein was posterior tibial vein (61.7%). In 91.25 %, more than one vein was involved. The major associated risk factors for DVT were patients who had undergone major operations (38.9%) and cancer patients (38.5%). CONCLUSION: DVT and other vascular lesions of lower limb in clinically suspicious patients can be reliably diagnosed by Doppler sonography.