Dural-Based Cavernous Malformation at the Cerebral Convexity: Report of Two Pediatric Patients

Li, Guichen; Zhai, Xuan; Zhang, Yang; Liang, Ping; Wu, Xuanxuan; Hou, Kun

doi:10.1016/j.wneu.2018.01.009

Cited by 4 publications

(6 citation statements)

References 18 publications

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“…Dural-based CMs that are located outside of the middle fossa are rarely associated with intracranial hemorrhage [ 28 ]. However, there have been reports of subdural hematoma in dural-based CMs located at the dural convexity [ 36 , 37 ].…”

Section: Discussionmentioning

confidence: 99%

Extra-Axial Cavernous Angioma: A Case Report and Review of the Literature

Hassanzadeh,

Gao,

Alvarado

et al. 2024

Neurology International

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Cavernous angiomas (CAs) are benign vascular malformations predominantly seen in the brain parenchyma and therefore referred to as intra-axial. Extra-axial dural-based cavernous angiomas, on the other hand, are rare vascular lesions found outside of the brain parenchyma. They occur in the middle fossa and may be easily misdiagnosed as meningiomas due to their extra-axial location. In addition, CAs that are located outside the middle fossa, such as in the convexity, have a better prognosis since they are more surgically accessible. Surgical resection is the main treatment of choice in CAs. However, other options, such as embolization and radiotherapy, may also be considered therapeutic choices or additive treatment options. The pathogenesis of CA and the involvement of other factors (genetics or environmental factors) are still unknown and require further investigation. We are presenting a young man who presented for evaluation of seizure-like events without any family history of neurologic conditions. The physical examination was unremarkable except for a slightly antalgic gait. Imaging studies showed an extra-axial left tentorial mass suggestive of a meningioma, hemangiopericytoma, or other extra-axial lesions. The lesion was resected where its vascular nature was mentioned initially, and the histology proved the diagnosis of cavernous angioma. Here we give an overview of the known pathogenesis, causes, clinical features, and diagnostic and therapeutic options in CA. Better knowledge about CA, its causes, clinical features, and treatment options would help clinicians in early diagnosis and patient management.

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Section: Discussionmentioning

confidence: 99%

Extra-Axial Cavernous Angioma: A Case Report and Review of the Literature

Hassanzadeh,

Gao,

Alvarado

et al. 2024

Neurology International

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“…There is few reported cavernoma presented as convexity dura-based location, mimicking meningioma; among the convexity-located group we found the parietal convexity is the common; [22][23][24][25] there are only two reported cases of occipital convexity. 32,33 In case of dura-based lesions that lack the other radiological feature of meningioma, like dura tail, and adjacent bone hyperostosis, other differential diagnosis should be considered rather than meningioma, like hemangiopericytoma, metastasis to dura, and even cavernoma.…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

Section: Discussion and Literature Reviewmentioning

confidence: 99%

Convexity Dura-Based Cerebral Cavernous Malformation Mimicking Meningioma: A Case Report and Literature Review

et al. 2022

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Cavernous angioma, cavernoma, cavernous hemangioma, also called cerebral cavernous malformation (when present in the brain), are benign vascular malformations, usually intraparenchymal; however, a few reported cases are in the extra-axial location—as middle cranial fossa, near the cavernous sinuses, and in the cerebellopontine angle—and are rarely reported as dura-based convexity lesion resembling meningioma. We report a giant dura-based, convexity, a cerebral cavernous malformation. We wish to notify the case as occurring at a rare location and a large-sized cerebral cavernous malformation. A case of young female presented with a long-standing history of headache. Computed tomography scan and magnetic resonance imagings (MRIs) suggested right occipital dura-based large mass lesion of approximately 5 cm in diameter. The lesion was excised and pathology studies confirmed the diagnosis of a cerebral cavernous malformation. A follow-up MRI confirmed total resection of the lesion and the patient had a smooth postoperative recovery.

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“…Hemorrhage is rare, but occasional cases presenting with acute subdural hematoma caused by hemorrhage from a dural-based CM located at the convexity of the dura mater have been reported. 5 , 9) Total surgical removal is the gold standard of treatment for dural-based CMs and allows definitive diagnosis. When total removal using duraplasty is achieved, adjuvant therapy is unnecessary.…”

Section: Discussionmentioning

confidence: 99%

“…3 – 9) Symptoms of dural-based CMs outside the middle fossa vary depending on the location and size of the lesion, and can include headaches, seizure, and focal neurological deficits, but rarely include intracranial hemorrhage. 5 , 9) Pregnant women release female hormones and several vascular growth factors that are known to induce morphological changes and angiogenesis of CMs. 10 , 11) These changes are more likely to increase the bleeding from CMs.…”

Section: Introductionmentioning

confidence: 99%

Dural-based Cavernous Malformation at the Temporal Convexity Presenting with Hemorrhage in a Pregnant Woman: Case Report

Ishii

Tanei

Kato

et al. 2021

NMC Case Report Journal

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Intracranial cavernous malformations (CMs) are benign vascular malformations that arise mostly within the brain parenchyma, but occasionally from the dura mater. Here, we report an extremely rare case of a 29-year-old pregnant woman presenting with hemorrhage in a dural-based CM at the temporal convexity. She presented with headache at 38 weeks of pregnancy. Imaging showed a hemorrhagic mass lesion in the left temporal lobe. Consciousness was clear, with no apparent neurological symptoms or headache. Her baby was delivered by emergency Caesarean section. Magnetic resonance (MR) imaging revealed an enhanced lesion around the hematoma and flow void appearances. Cerebral angiography confirmed the left middle meningeal artery feeding the lesion with apparent contrast medium pooling. Surgical removal of the lesion as a single block was performed. Histological examinations were consistent with CM. The lesion was located outside the brain and attached to the dura mater of the convexity, so the final diagnosis was dural-based CM. The patient was discharged home with her baby without any neurological deficits, and no recurrence has been seen for 2 years. Dural-based CM at the temporal convexity was detected, presenting as headache induced by hemorrhage during pregnancy. The relationship between bleeding of the lesion and pregnancy remains unclear, but female hormones and vascular growth factors during pregnancy can induce morphological changes and angiogenesis in CMs.

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Dural-Based Cavernous Malformation at the Cerebral Convexity: Report of Two Pediatric Patients

Cited by 4 publications

References 18 publications

Extra-Axial Cavernous Angioma: A Case Report and Review of the Literature

Extra-Axial Cavernous Angioma: A Case Report and Review of the Literature

Convexity Dura-Based Cerebral Cavernous Malformation Mimicking Meningioma: A Case Report and Literature Review

Dural-based Cavernous Malformation at the Temporal Convexity Presenting with Hemorrhage in a Pregnant Woman: Case Report

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