Durchführung und Indikationen der quantitativen Sialoszintigraphie

Kh, Bohuslavizki; Brenner, Winfried; Klutmann, Susanne; Tinnemeyer, S.; Ja, Werner; Mester, János; Clausen, M.; Henze, Eberhard

doi:10.1055/s-2007-997489

Cited by 8 publications

(3 citation statements)

References 17 publications

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“…The rarely indicated scintigraphy with Tc-99 pertechnetate is available as a functional imaging method which provides very good assessability of salivary gland functioning but has only limited morphological significance [11]. It is not used in cases of acute obstructive sialadenitis but rather in posttherapeutic situations, for example after the treatment of obstructive sialadenitis, external radiation, or radiotherapy [12].…”

Section: Further Proceduresmentioning

confidence: 99%

Updated S2K AWMF Guideline for the Diagnosis and Follow-up of Obstructive Sialadenitis – Relevance for Radiologic Imaging

Vogl

Beutner

Geisthoff

et al. 2014

Fortschr Röntgenstr

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The interdisciplinarily developed German S2k AWMF guideline for the treatment of obstructive sialadenitis represents a new standard in the guideline program of the AWMF, the German Society for Consultants and the clinical disciplines working in the field of diseases of the head and neck region. In the last few years new diagnostic and therapeutic possibilities have been established in obstructive chronic Sialadenitis offering individually optimized therapeutic strategies. Only a few years ago extirpation of the whole affected gland was the only relevant therapy option. Nowadays therapeutic options such as interventional sialendoscopy and extracorporeal shock-wave lithotripsy (ESWL) are available in combination with marsupialization or incision of the duct. If possible the focus is on preserving the main glandular duct. In the following article the relevant aspects for the diagnostic radiologic procedures are presented. Key Points: ??Radiological methods are a noninvasive alternative to sialendoscopy and should be given preference in the case of acute inflammation. ??Sonography is the radiological method of first choice. ??The use of intravenous or intraductal contrast agent is not necessary due to the prestenotically dilated duct system. Citation Format: ??Vogl TJ, Al-Nawas B, Beutner D et?al. Updated S2K AWMF Guideline for the Diagnosis and Follow-up of Obstructive Sialadenitis ? Relevance for Radiologic Imaging. Fortschr R?ntgenstr 2014; 186: 843???846

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Section: Further Proceduresmentioning

confidence: 99%

Updated S2K AWMF Guideline for the Diagnosis and Follow-up of Obstructive Sialadenitis – Relevance for Radiologic Imaging

Vogl

Beutner

Geisthoff

et al. 2014

Fortschr Röntgenstr

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“…This demonstrates that especially parotid glands seem to be organs at risk for RIT, rather than SMGs. Findings for all glands pre-and post-interventional including ER after excretion stimulus are demonstrated in ▶ Table 3 with corresponding p-values and standard of reference as stated by Bohuslavizki et al (19).…”

Section: Salivary Gland Scintigrammentioning

confidence: 79%

“…Regions of interest (ROI) were calculated for each parotid and submandibular gland, and excretion rates after oral administration of lemon juice were calculated for each gland. In order to classify the function of each gland, measured maximal uptake during dynamic imaging (U max ) and excretion rate (ER) after oral stimulation were compared to a standard of reference published in a review article by Bohuslavizki et al (19).…”

Section: Methodsmentioning

confidence: 99%

Impact of sialendoscopy on improving health related quality of life in patients suffering from radioiodineinduced xerostomia

et al. 2018

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Summary Introduction: Xerostomia following radioiodine therapy (RIT) in patients suffering from differentiated thyroid cancer is a common side effect in 2 % to 67 % of patients treated with radioiodine (I-131). In order to evaluate the impact of sialendoscopy on health related quality of life (HRQOL) in patients suffering from therapy induced sialadenitis and xerostomia, we analyzed findings from two dedicated questionnaires (Xerostomy Questionnaire XQ and Xerostomy Inventory XI) in patients before and three months after sialendoscopy. Procedures: In total, 12 patients suffering from differentiated thyroid carcinoma (10 women and 2 men) were evaluated. All patients had experienced conservative management. Patients were offered a sialendoscopy procedure if no major contradictions were present. Patients who denied the procedure formed the control group. Pre- and (three months) postoperative HRQOL was measured with the Patient Reported Outcome Measures (PROM) Xerostomia Questionnaire (XQ) and the Xerostomia Inventory (XI), as well as by a pre- and post-interventional salivary gland scintigram. Patients were graded according to their sialendoscopical findings. Results: Interventional group presented with significant improvements in HRQOL measurements regarding XQ and XI-scores three months postoperatively. Control group showed no significant changes in the XQ or the XI scores. Number of RIT and cumulative activity of I-131 did not correlate with higher disease grade in regards to sialendoscopical findings nor did it correlate with higher XQand XI scores. Pre- and post-interventional salivary gland scintigram stated that parotid glands are more severely damaged than submandibular glands (SMG), but no significant scintigraphically changes could be detected after sialendoscopy. Conclusion: Sialendoscopy in patients suffering from therapy induced sialadenitis and xerostomia seems to be beneficial when evaluating the impact on HRQOL. Functional parameters measured by salivary gland scintigram did not show significant changes in post-interventional scintigrams.

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Amifostine is a Potent Radioprotector of Salivary Glands in Radioiodine Therapy

et al. 2005

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Durchführung und Indikationen der quantitativen Sialoszintigraphie

Abstract: Salivary gland scintigraphy is a study that is easily performed and well tolerated by the patient. It yields quantitative parameters for parenchymal function and excretion fraction.

Cited by 8 publications

References 17 publications

Updated S2K AWMF Guideline for the Diagnosis and Follow-up of Obstructive Sialadenitis – Relevance for Radiologic Imaging

Updated S2K AWMF Guideline for the Diagnosis and Follow-up of Obstructive Sialadenitis – Relevance for Radiologic Imaging

Impact of sialendoscopy on improving health related quality of life in patients suffering from radioiodineinduced xerostomia

Amifostine is a Potent Radioprotector of Salivary Glands in Radioiodine Therapy

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