Dynamic contrast-enhanced and ultra-high-resolution breast MRI at 7.0 Tesla

Stehouwer, Bertine L.; Klomp, Dennis W. J.; Bosch, Maurice A.A.J. van den; Korteweg, Mies A.; Gilhuijs, Kenneth G. A.; Witkamp, Arjen J.; Diest, Paul J. van; Houwert, Karel A. F.; Kemp, Wybe J. M. van der; Luijten, Peter R.; Mali, Willem P.Th.M.; Veldhuis, Wouter B.

doi:10.1007/s00330-013-2985-9

Cited by 17 publications

(19 citation statements)

References 17 publications

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“…Additionally, studies indicate that in women recently diagnosed with unilateral breast cancer, additional cancer lesions are sometimes detected in the contralateral breast [25]. Several 7T breast studies have indicated a need for bilateral coil design [8], [11]. On the other hand, in some applications, e.g., proton decoupling in second-nuclei applications, a unilateral coil may be preferred, since it enables judicious use of the available total proton decoupling power in a single breast [26]–[28].…”

Section: Introductionmentioning

confidence: 99%

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation

Cui

Bosshard

Rispoli

et al. 2015

IEEE Trans. Biomed. Eng.

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In high-field magnetic resonance imaging, the radio frequency wavelength within the human body is comparable to anatomical dimensions, resulting in B1 inhomogeneity and nonuniform sensitivity patterns. Thus, this relatively short wavelength presents engineering challenges for RF coil design. In this study, a bilateral breast coil for 1H imaging at 7 T was designed and constructed using forced-current excitation. By forcing equal current through the coil elements, we reduce the effects of coupling between the elements to simplify tuning and to ensure a uniform field across both breasts. To combine the benefits of the higher power efficiency of a unilateral coil with the bilateral coverage of a bilateral coil, a switching circuit was implemented to allow the coil to be reconfigured for imaging the left, right, or both breasts.

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Section: Introductionmentioning

confidence: 99%

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation

Cui

Bosshard

Rispoli

et al. 2015

IEEE Trans. Biomed. Eng.

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“…Lymph node spiculation, typically evaluated in histology, is linked to malignancy and as an indication of extranodal extension, linked to aggressive tumor types with poor prognosis . Wendl et al reported on 3T DCE of lymph nodes in the neck; with 1 × 1 × 2 mm voxels, the authors note that partial volume effects degrade the ability to reliably differentiate malignant from benign lymph nodes with <10 mm diameter, and SNR limits the ability to improve spatial resolution. We demonstrate that our coil is capable of resolving lymph nodes with 3‐mm cross‐sections.…”

Section: Discussionmentioning

confidence: 99%

MRI and ³¹ P magnetic resonance spectroscopy hardware for axillary lymph node investigation at 7T

et al. 2014

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“…Advantages of performing MR at ultrahigh field strengths include a higher SNR and a higher chemical shift . The first advantage can be used to increase spatial resolution, which has been shown to be feasible in a clinical setting and might have potential for earlier and better diagnosis . Additionally, a better spatial resolution enables the assessment of tumor heterogeneity .…”

Section: Introductionmentioning

confidence: 99%

Correcting time‐intensity curves in dynamic contrast‐enhanced breast MRI for inhomogeneous excitation fields at 7T

Rijssel

Pluim

Chan

et al. 2019

Magnetic Resonance in Med

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Purpose: Inhomogeneous excitation at ultrahigh field strengths (7T and above) compromises the reliability of quantified dynamic contrast-enhanced breast MRI. This can hamper the introduction of ultrahigh field MRI into the clinic. Compensation for this non-uniformity effect can consist of both hardware improvements and postacquisition corrections. This paper investigated the correctable radiofrequency transmit (B + 1 ) range post-acquisition in both simulations and patient data for 7T MRI. Methods: Simulations were conducted to determine the minimum B + 1 level at which corrections were still beneficial because of noise amplification. Two correction strategies leading to differences in noise amplification were tested. The effect of the corrections on a 7T patient data set (N = 38) with a wide range of B + 1 levels was investigated in terms of time-intensity curve types as well as washin, washout and peak enhancement values. Results: In simulations assuming a common amount of T 1 saturation, the lowest B + 1 level at which the SNR of the corrected images was at least that of the original precontrast image was 43% of the nominal angle. After correction, time-intensity curve types changed in 24% of included patients, and the distribution of curve types corresponded better to the distribution found in literature. Additionally, the overlap between the distributions of washin, washout, and peak enhancement values for grade 1 and grade 2 tumors was slightly reduced. Conclusion: Although the correctable range varies with the amount of T 1 saturation, post-acquisition correction for inhomogeneous excitation was feasible down to B + 1 levels of 43% of the nominal angle in vivo. K E Y W O R D S 7T, B + 1 mapping, breast, DCE-MRI, flip-angle correction, RF field inhomogeneity | 1001 van RIJSSEL Et aL.

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Dynamic contrast-enhanced and ultra-high-resolution breast MRI at 7.0 Tesla

Abstract: • Magnetic resonance imaging is important in the evaluation of breast cancer. • Recently, 7-T MRI has become available. • The 7-T dynamic contrast-enhanced breast MRI is feasible in patients. • The 7-T breast examinations are amenable to evaluation according to BI-RADS.

Cited by 17 publications

References 17 publications

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation

MRI and ³¹ P magnetic resonance spectroscopy hardware for axillary lymph node investigation at 7T

Correcting time‐intensity curves in dynamic contrast‐enhanced breast MRI for inhomogeneous excitation fields at 7T

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Dynamic contrast-enhanced and ultra-high-resolution breast MRI at 7.0 Tesla

Abstract: • Magnetic resonance imaging is important in the evaluation of breast cancer. • Recently, 7-T MRI has become available. • The 7-T dynamic contrast-enhanced breast MRI is feasible in patients. • The 7-T breast examinations are amenable to evaluation according to BI-RADS.

Cited by 17 publications

References 17 publications

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation

MRI and 31 P magnetic resonance spectroscopy hardware for axillary lymph node investigation at 7T

Correcting time‐intensity curves in dynamic contrast‐enhanced breast MRI for inhomogeneous excitation fields at 7T

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Product

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MRI and ³¹ P magnetic resonance spectroscopy hardware for axillary lymph node investigation at 7T