Dynamic Covalent Nanoparticle Building Blocks

Abstract

Rational and generalisable methods for engineering surface functionality will be crucial to realising the technological potential of nanomaterials. Nanoparticle‐bound dynamic covalent exchange combines the error‐correcting and environment‐responsive features of equilibrium processes with the stability, structural precision, and vast diversity of covalent chemistry, defining a new and powerful approach for manipulating structure, function and properties at nanomaterial surfaces. Dynamic covalent nanoparticle (DCNP) building blocks thus present a whole host of possibilities for constructing adaptive systems, devices and materials that incorporate both nanoscale and molecular functional components. At the same time, DCNPs have the potential to reveal fundamental insights regarding dynamic and complex chemical systems confined to nanoscale interfaces.

Programmable dynamic covalent nanoparticle building blocks with complementary reactivity

“…We have recently implemented dynamic covalent reactions in nanoparticle-bound settings 4 as a exible means to reversibly alter the constitution of nanoparticle-stabilizing molecular monolayers, 5 to tune the composition of mixed-ligand monolayersand consequently nanoparticle properties 6 and to direct covalent assembly-disassembly of nanoparticle aggregates. 7 Meanwhile, others have exploited reversible covalent reactions to achieve nanoparticle-bound monolayer constitutions that adapt to noncovalently bound templates, 8 or to stabilize nanoparticle assemblies and surface attachment.…”

Molecular Networks in Dynamic Multilevel Systems

“…Dynamic covalent exchange has been applied to tunet he interfacial properties of nanoparticles. [34,35] The combination of orthogonal reactions could enhancet he potential of this approach.…”

Novel Sensing Strategies Based on Monolayer Protected Gold Nanoparticles for the Detection of Metal Ions and Small Molecules

“…The use of DCC chemistry has been also used by Kay and coworkers to modify the physicochemical properties of gold nanoparticles . We highlight dynamic covalent NPs because the use of these novel stimuli‐responsive nanomaterials can open the possibility to create sensing systems that detect multi‐elements simultaneously …”