Dynamic imaging of hyperpolarized3He distribution in rat lungs using interleaved-spiral scans

Viallon, Magalie; Berthezène, Yves; Callot, Virginie; Bourgeois, Marc; Humblot, H.; Briguet, A.; Crémillieux, Yannick

doi:10.1002/1099-1492(200006)13:4<207::aid-nbm641>3.0.co;2-g

Cited by 44 publications

(7 citation statements)

References 23 publications

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“…By using a “sliding window” reconstruction (61), these sampling strategies result in a smoother depiction of motion, with a higher refresh rate than that obtained with Cartesian‐based sampling methods. Initial animal experiments showed promising results using both radial projection (62) and interleaved‐spiral cine acquisitions (63) of inhaled 3‐He gas.…”

Section: Hyperpolarized 3‐helium Mr Imagingmentioning

confidence: 99%

Functional MRI of the lung using hyperpolarized 3‐helium gas

Beek¹,

Wild²,

Kauczor³

et al. 2004

Magnetic Resonance Imaging

248

210

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Lung imaging has traditionally relied on x-ray methods, since proton MRI is limited to some extent by low proton density in the lung parenchyma and static field inhomogeneities in the chest. The relatively recent introduction of MRI of hyperpolarized noble gases has led to a rapidly evolving field of pulmonary MRI, revealing functional information of the lungs, which were hitherto unattainable. This review article briefly describes the physical background of the technology, and subsequently focuses on its clinical applications. Four different techniques that have been used in various human investigations are discussed: ventilation distribution, ventilation dynamics, and small airway evaluation using diffusion imaging and oxygen uptake assessment.

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Section: Hyperpolarized 3‐helium Mr Imagingmentioning

confidence: 99%

Functional MRI of the lung using hyperpolarized 3‐helium gas

Beek¹,

Wild²,

Kauczor³

et al. 2004

Magnetic Resonance Imaging

248

210

View full text Add to dashboard Cite

show abstract

“…One method for reducing diffusion weighting is to use projection reconstruction (PR) approaches, which collect the center of k‐space in a non‐Cartesian fashion immediately following the excitation pulse, before significant signal loss occurs. Both PR and spiral/cone acquisitions have been demonstrated to reduce diffusion weighting for HP 3 He MRI of rodent lungs . In addition to significantly reducing diffusion weighting, PR approaches also provide very short echo times (>200 µs), which reduces

{normalT}_{2}^{*}

weighting, leading to images that are strongly weighted by gas density.…”

Section: Introductionmentioning

confidence: 99%

High spatial resolution hyperpolarized ³He MRI of the rodent lung using a single breath X‐centric gradient‐recalled echo approach

Ouriadov

Santyr

2017

Magnetic Resonance in Med

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“…Da in jedem Bild jedoch nur ein kleiner Teil der k-RaumDaten neu aufgenommen wurde, handelt es sich nicht um eine echte zeitliche Auflösung von 10 ms. Durch die hö-here Aktualisierungsrate als bei kartesischen Ausleseverfahren liegt vielmehr ein "weicherer" Übergang der Einzelbilder vor, sie stellt eine elegante Art der zeitlichen Interpolation dar. Bisherige Messungen an Mensch und Tier haben sowohl bei der Radialprojektion [48,49] als auch bei der zeitlich über-lappenden Spiralakquisition [50,51] von 3 He vielversprechende Ergebnisse erbracht [52]. Die Spiraltechnik akquiriert hierbei keine Projektionsbilder (Abbildung 3), sondern ermöglicht auch die schichtselektive Messung mit z.B.…”

Section: Dynamische Ventilationunclassified

Funktionelle MRT der Lunge unter Verwendung von hyperpolarisiertem 3Helium-Gas

Gast

Morbach²,

Kauczor

et al. 2005

Med Klin

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Lung imaging is traditionally done using X-ray-based methods, since MRI is limited by low proton density as well as inherent magnetic field inhomogeneities of the lung tissue. After introduction of MRI using hyperpolarized noble gases, a totally new field of MRI of the chest has rapidly evolved. These techniques reveal new functional information of the lungs, which could not be obtained before. The first part of this review describes the underlying MR technology explaining distribution of static ventilation, dynamic distribution of ventilation, lung microstructure (apparent diffusion coefficient [ADC]), measurement of oxygen partial pressure (pO(2)), and safety. The clinical potential is afterwards demonstrated in the second part. Therefore, the effort in normal lungs and the mainly focused diseases chronic obstructive pulmonary disease (COPD), smoker's lung, cystic fibrosis, asthma, lung transplantation, and pulmonary embolism are reported.

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Dynamic imaging of hyperpolarized3He distribution in rat lungs using interleaved-spiral scans

Cited by 44 publications

References 23 publications

Functional MRI of the lung using hyperpolarized 3‐helium gas

Functional MRI of the lung using hyperpolarized 3‐helium gas

High spatial resolution hyperpolarized ³He MRI of the rodent lung using a single breath X‐centric gradient‐recalled echo approach

Funktionelle MRT der Lunge unter Verwendung von hyperpolarisiertem 3Helium-Gas

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Dynamic imaging of hyperpolarized3He distribution in rat lungs using interleaved-spiral scans

Cited by 44 publications

References 23 publications

Functional MRI of the lung using hyperpolarized 3‐helium gas

Functional MRI of the lung using hyperpolarized 3‐helium gas

High spatial resolution hyperpolarized 3He MRI of the rodent lung using a single breath X‐centric gradient‐recalled echo approach

Funktionelle MRT der Lunge unter Verwendung von hyperpolarisiertem 3Helium-Gas

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High spatial resolution hyperpolarized ³He MRI of the rodent lung using a single breath X‐centric gradient‐recalled echo approach