Dynamic parameters of homeostasis under the influence of antiaggregant treatment in patients with atrial fibrillation and metabolic syndrome

Abstract

The condition of coagulation and platelet hemostasis in 125 patients with atrial fibrillation (AF) and with metabolic syndrome (MS) has been analysed. Сoagulation and platelet hemostasis in 125 patients with AF and MS under treatment with acetylsalicylic acid (ASA) (group 1), omega-3 polyunsaturated fatty acids (omega-3 PUFAs) (group 2) and ASA with L-arginine (3 group) during 2 months were measured. It was established that omega-3 PUFAs are more effective compared with ASA/aspirin with L-arginine and it promotes normalization of fibrinogen, soluble fibrin-monomer complexes (SFMK), D-dimer and improves the platelet aggregative activity (PAA).