Dynamic Simulation and Hemolysis Evaluation of the Regurgitant Flow over a Tilting-Disc Mechanical Heart Valve in Pulsatile Flow

Abstract

<p class="MsoNormal" style="text-align:justify;"> <span lang="EN-US">Regurgitation in the heart diastolic phase represents a critical flow condition associated with many heart valve design considerations. The finite volume method, the Low-Reynolds-Number <i>k-ω</i> turbulent model and sliding mesh model are employed to solve and compare the complex flow field and the torque in each case. The end results expected from a cardiovascular CFD analysis are not limited only to the flowfield investigations. More importantly, it needs an evalua</span><span lang="EN-US">tion criterion to judge if the design is acceptable as considered from a broader blood cell damage or activation perspec</span><span lang="EN-US">tive. In this study, blood cell damage index developed based on stress-time empirical rule and Lagrangian particle tracking is introduced to assess the viscous and turbulence-induced stresses effect to the blood cells. </span> </p

Lagrangian Postprocessing of Computational Hemodynamics

“…Similar to platelet activation potential, different models have been proposed to study hemolysis taking the exposure time and stress level into account [57]. Ventricular assist devices (blood pumps) [3, 135, 136, 152, 153, 109], and MHVs [34, 132, 35, 63] have been common applications of hemolysis studies.…”