The direction of ground-based interference reaching the satellite is generally very close to the spot beam of the satellite. The traditional array anti-jamming method may cause significant loss to the uplink signal while suppressing the interference. In this paper, an aperiodic multistage array is used, and a subarray aperiodic distribution optimization scheme based on parallel differential evolution is proposed, which effectively improves the beam resolution and suppresses the grating lobe. On this basis, a two-stage signal processing method is used to suppress interference. Finally, the comprehensive performance of the proposed scheme is evaluated and verified.