“…In this case fitting may be still possible but considerably more complicated. But if adsorption is irreversible, as may be the case for some proteins (see, e.g., 21,27), no such relation can be obtained by fitting of the experimental data, and the existing theoretical models are not adequate for a sufficiently general prediction of protein film behavior. Therefore, computer simulations are recommended only for some situations, where a functional relation between measurement and control variable can easily be obtained.…”