Dynamics of changes in the indices of the level of endogenous intoxication in patients with alcoholic lesions of the liver

Abstract

Changes of the indices of the level of endogenous intoxication in 122 patients with an alcoholic lesion of the liver have been studied. It has been established that a high level of endogenous intoxication is identified in these patients connected with a reduction of the concentration of endogenous albumin in the peripheral blood, due to an accumulation of molecules of medium mass, a decrease of the effective concentration of albumin and the toxin-binding ability of albumin.