Dysnatremias, Mortality, and Kidney Failure in CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study

Hassanein, Mohamed; Arrigain, Susana; Schold, Jesse D.; Nakhoul, Georges; Navaneethan, Sankar D.; Mehdi, Ali; Sekar, Arjun; Tabbara, Jad; Taliercio, Jonathan J.

doi:10.1016/j.xkme.2022.100554

Cited by 7 publications

(3 citation statements)

References 50 publications

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“…The observed scenario might be related to various factors and one of these might be that the manual nature of CAPD may lead to variations in the adequacy of dialysis and the clearance of waste products and toxins [21], which can impact overall health and survival. In addition, the frequent exchanges in CAPD can cause fluctuations in fluid and electrolyte levels [22,23], potentially leading to imbalances and associated complications. Finally, APD may provide greater convenience and ease of adherence, ensuring more consistent and regular dialysis sessions [24].…”

Section: Discussionmentioning

confidence: 99%

Ten-Year Single-Center Study Examining Patient Survival after Commencing Long-Term Peritoneal Dialysis

Venegas-Ramírez,

Barrios-Mora,

Ríos-Bracamontes

et al. 2023

JCM

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In patients with end-stage kidney disease (ESKD), peritoneal dialysis (PD) is increasingly being adopted in developing nations due to its cost-effectiveness and advantages as a home-based treatment. However, the survival outcomes of chronic PD patients in Mexico, where the burden of ESKD is high, remain poorly understood. This study aimed to assess the survival experience of long-term PD patients and evaluate its determinants. A single-center cohort study collected clinical and epidemiological data for long-term PD initiations between February 2013 and January 2023. The analysis, which utilized Kaplan–Meier and Cox proportional hazard regression methods, included data from 370 patients. The overall mortality rate was 4.7 per 1000 person-months, with a significant decrease in survival rates observed between months 24 and 36 post-PD initiation. Older age at PD initiation and the use of continuous ambulatory peritoneal dialysis, as compared to the automated modality, were associated with an increased risk of mortality. The study provides valuable insights into the survival outcomes of chronic PD patients in Mexico and suggests the need to optimize treatment strategies to enhance long-term prognoses for patients with ESKD. Further research is needed to better understand the factors influencing survival in this population.

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Section: Discussionmentioning

confidence: 99%

Ten-Year Single-Center Study Examining Patient Survival after Commencing Long-Term Peritoneal Dialysis

Venegas-Ramírez,

Barrios-Mora,

Ríos-Bracamontes

et al. 2023

JCM

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“…Hyponatraemia is a common electrolyte abnormality seen in ESLD, 16 and is associated with worse mortality in CKD. 17 Sodium levels can rise due to improved liver function post-transplant. The anaesthesiologist can attempt to avoid substantial changes in sodium levels, but this might not always be possible because of the need for intravenous fluids and blood products.…”

Section: Liver Transplantation Surgery and Hyponatraemiamentioning

confidence: 99%

Renal Replacement Therapy During Liver Transplant Surgery

Sekar,

Reddy,

Gandhi

et al. 2024

EMJ

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Liver transplant is the treatment available for eligible patients with end-stage liver cirrhosis. Acute kidney injury and electrolyte abnormalities are associated with liver disease and can be exacerbated by surgery. Intraoperative renal replacement therapy has been tried in some large centres. The authors discuss the physiological changes and complications during liver transplant surgery, and review literature on the safety, feasibility, benefits, and drawbacks of intraoperative renal replacement therapy during liver transplant surgery.

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“…For instance, sodium retention can induce hypertension and edema, while hyperkalemia can have detrimental effects on cardiac function, posing potential life-threatening risks. 11,[53][54][55][56] Hyperphosphatemia and hypocalcemia can lead to abnormal mineral metabolism and osteoporosis. 9 Abnormal blood potassium, hyponatremia, and hypocalcemia can give rise to symptoms like muscle twitching, limb weakness, and numbness.…”

Section: Fluid and Electrolyte Balancementioning

confidence: 99%

Involuntary Falls in Patients with Chronic Kidney Diseases on Nephrology Wards: Research Advances and Future Perspectives

Liao,

Wang,

Sui

et al. 2024

NRR

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Background: Nephrology nursing faces an inevitable challenge when it comes to falls. This study aims to review existing literature on falls in chronic kidney disease (CKD) patients and to discuss potential solutions. Methods: This review explores the characteristics and causes of falls in CKD patients, elucidate the underlying mechanisms, shares better nursing practices, and discusses both current prevention strategies as well as potential future interventions. Results: CKD patients often experience consciousness impairment and motor dysfunction due to factors such as muscle atrophy, nerve damage, malnutrition, anemia, fluid-electrolyte imbalances, hormonal disorders, and dialysis. Additionally, this study not only shares insights from nursing experience with these patients, but also reviews current evidence-based fall prevention strategies and proposes potential new interventions that could be tested in future research. Conclusion: CKD may increase the risk of involuntary falls in patients due to consciousness impairment and motor dysfunction. Advocating for a standardized expert consensus on fall risk assessment and comprehensive care for CKD patients would enhance the nursing framework in nephrology wards and help patients decrease their fall risk and elevate their quality of life.

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Dysnatremias, Mortality, and Kidney Failure in CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study

Cited by 7 publications

References 50 publications

Ten-Year Single-Center Study Examining Patient Survival after Commencing Long-Term Peritoneal Dialysis

Ten-Year Single-Center Study Examining Patient Survival after Commencing Long-Term Peritoneal Dialysis

Renal Replacement Therapy During Liver Transplant Surgery

Involuntary Falls in Patients with Chronic Kidney Diseases on Nephrology Wards: Research Advances and Future Perspectives

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