Dysplasia and Malignancy in Endocervical Polyps

Berzolla, Catherine E.; Schnatz, Peter F.; O’Sullivan, David; Bansal, Renu; Mandavilli, Srinivas; Sorosky, Joel I.

doi:10.1089/jwh.2007.0408

Cited by 43 publications

(46 citation statements)

References 9 publications

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“…They are more frequent in parous women over 20 years of age and most of them (60-70%) are asymptomatic and found on routine speculum examination of cervix. [2][3][4][5][6][7] They can however cause symptoms such as intermenstrual, postcoital and postmenopausal bleeding as well as vaginal discharge. It is common practice to remove these polyps whenever they are identified and the main reason for this is the concern over the potential for malignant transformation.…”

Section: Introductionmentioning

confidence: 99%

“…congestion or cervical vasculature and/or an abnormal local response to estrogen stimulation. 13,15 Endometrial polyps consist of endometrial glands, stroma and blood vessels. 16 Many clinicians believe that routine removal of polyps is reasonable because they are easy to remove, unlikely to resolve, may become symptomatic and it is not known if they are likely to progress to malignancy.…”

Section: Introductionmentioning

confidence: 99%

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Clinicopathological analysis of cervical polyps

Gopalan

Rajendiran

Ranganathan

2017

Int J Reprod Contracept Obstet Gynecol

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Background: Cervical polyps are the commonest cervical lesions and occur in about 2-5% of women. It is common practice to remove these polyps whenever they are identified and the main reason for this is the concern over the potential for malignant transformation. This study was done to analyse the spectrum of histopathological diagnosis in cases of cervical polyps and to identify focus of malignancy if present. This would help us to improve further management of cases of symptomatic and asymptomatic cervical polypsMethods: This study was conducted in the department of Obstetrics and Gynecology in a tertiary care teaching hospital over a period of two years. Women with a polypoidal growth from the cervix visualized on per speculum examination were included in the study. Polypectomy was done and the specimen sent for histopathological examination and the data analysed.Results: Total of 107 women was included in the study. Most of the women (47.7%) were in the age group 40-49 years. Endocervical mucous polyp was found to be the most common lesion (50.5%) followed by benign endometrial polyp (21.5%), and leiomyomatous polyp in 13.1%. There were no foci of malignancy identified in any of these polyps.Conclusions: As the incidence of malignancy in endocervical polyp is very low, it is suggested that in cases of asymptomatic polyps, there is a role for expectant management with no intervention and these patients can be followed up leading to significant savings in health resources

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinicopathological analysis of cervical polyps

Gopalan

Rajendiran

Ranganathan

2017

Int J Reprod Contracept Obstet Gynecol

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“…[1][2][3]5 Most of the studies in the literature focusing on etiological factors are related with endometrial polyps. Hormonal factors, obesity, late menopause, hormone replacement therapy, polycystic ovary syndrome and Tamoxiphene (Nolvadex, AstraZeneca, UK) use are thought to play an important role in endometrial polyps.…”

Section: Discussionmentioning

confidence: 99%

“…Although cervical polyps are frequently observed, the etiology is not yet fully clear. [1][2][3]5 To date, there are limited published studies about cervical polyps as well as the research for risk factors that contribute to the etiology. Chronic inflammation (chronic cervicitis, foreign bodies), localised collection/congestion of cervical vasculature, an abnormal local response to hormone stimulation, and other theories have been proposed to explain their pathogenesis.…”

mentioning

confidence: 99%

“…Chronic inflammation (chronic cervicitis, foreign bodies), localised collection/congestion of cervical vasculature, an abnormal local response to hormone stimulation, and other theories have been proposed to explain their pathogenesis. 1,3 It was reported that diabetes mellitus (DM), hypertension (HT), and obesity may be risk factors for endometrial polyps even if it is not yet studied whether these conditions primarily influence the development of cervical polyps. [6][7][8] To address this area, this study focused on whether diabetes, hypertension, and obesity can be considered risk factors for cervical polyps.…”

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confidence: 99%

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Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?

Uçar¹,

Uçar²,

İlhan³

et al. 2016

Turkiye Klinikleri J Gynecol Obst

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226ervical polyps are common benign neoplasms of the cervix in adult women.1 They are believed to develop as a result of focal hyperplasia. They usually develop in multiparous women during the fifth Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To investigate whether diabetes, hypertension, and obesity can be considered risk factors for cervical polyps. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The hospital-based case-control study was carried out. We retrospectively reviewed the records of 307 consecutive patients with cervical polyps. A control group consisting of 3 women per case-matched by the same age, same parity, same menopausal status and the same presenting symptoms. These groups were compared with respect of diabetes, hypertension and obesity prevalence. R Re es su ul lt ts s: : The study included a total of 212 patients eligible for analysis in cervical polyp group, and a matched control group consisting of 636 women without cervical polyp. Women with cervical polyp had higher body mass index than the controls, but the difference was not statistically significant (p=0.72). The prevalence of obesity was significantly higher in the cervical polyp group than the controls (p=0.016). A statistically significant correlation was found between obesity and cervical polyps (OR: 1.351, CI: 1.062-1,718). There was no significant difference between the groups with respect to the prevalence of diabetes (p=0.795) and hypertension (p=0.703). C Co on nc cl lu us si io on n: : Obesity appears to be a risk factor for cervical polyps. Obese women should receive special attention for potential coexistence of cervical polyps as part of their gynecological evaluation. This study supports the importance of weight management for the preventive plan of cervical polyps.K Ke ey y W Wo or rd ds s: : Cervix uteri; polyps; diabetes mellitus; hypertension; obesity Ö ÖZ ZE ET T A Am ma aç ç: : Diyabet, hipertansiyon ve obezitenin servikal polipler için risk faktörü olup olmadığını araştırmaktır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Hastane tabanlı vaka-kontrol çalışması oluşturuldu. 307 ardışık servikal polip hastasının kayıtları retrospektif olarak değerlendirildi. Her servikal polip hastası için, aynı yaş, aynı parite, aynı menopozal durumda ve aynı başvuru şikayeti ile gelen 3 kontrol hastası belirlendi. Gruplar hipertansiyon, diyabet ve obezite prevalansı açısından karşılaştırıldı. B Bu ul lg gu ul la ar r: : Çalışma kriterlerine uygun servikal polibi olan 212 hasta vaka grubuna ve servikal polibi olmayan eşleştirilmiş 636 hasta kontrol grubuna dahil edildi. Servikal polip hastalarının beden kitle indeksi, kontrol grubundan daha fazlaydı, ancak bu fark istatistiksel anlamlı değildi (p=0,72). Obezite prevalansı servikal polip grubunda, kontrol grubundan istatistiksel olarak anlamlı düzeyde yüksek bulundu (p=0,016). Obezite ve servikal polipler arasında istatistiksel anlamlı düzeyde korelasyon saptandı (OR: 1,351, ...

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Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort study

Hirayama

Ebina

Kato

et al. 2021

Intl J Gynecology & Obste

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Objective: To determine the association between cervical polyps in early pregnancy and late abortion and spontaneous preterm birth (SPTB). We also aimed to explore the relationship between cervical polyps and cervical insufficiency in the second trimester. Methods:We conducted a retrospective cohort study of 2941 singleton pregnant women between January 2010 and December 2015. The frequency of late abortion and SPTB (before 28, 34, or 37 weeks of pregnancy) was compared between the two groups of 142 (4.8%) patients who had cervical polyps early in the pregnancy (P group) and 2799 who did not (non-P group). Multivariate analysis was performed to identify risk factors for late abortion and SPTB. Results:The incidence of late abortion and SPTB was significantly higher in the P group than in the non-P group. Cervical polyps in early pregnancy were selected as independent risk factors for late abortion and SPTB before 28, 34, or 37 weeks of pregnancy. The P group had a significantly higher rate of cases requiring therapeutic cervical cerclage than the non-P group. Conclusion:Cervical polyps in early pregnancy are risk factors for late abortion and SPTB. They are also associated with the occurrence of cervical insufficiency.

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Dysplasia and Malignancy in Endocervical Polyps

Cited by 43 publications

References 9 publications

Clinicopathological analysis of cervical polyps

Clinicopathological analysis of cervical polyps

Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?

Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort study

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