PurposeTo identify and analyze the relevant themes in the literature on digital transformation and internationalization, revealing opportunities for future studies.Design/methodology/approachA systematic literature review was developed using the Scopus and Web of Science databases. Initially, 156 publications were identified. Based on inclusion/exclusion criteria, a final sample of 74 articles was reached. A bibliometric and qualitative analysis were developed.FindingsEight main themes related to internationalization, such as internationalization strategy, internationalized companies, marketing-related issues, export, global supply chain, entrepreneurship and new ventures, SMEs internationalization and internationalization of educational institutions, were identified. Eight main themes related to digital transformation were also identified, including internationalization drivers, digital technologies, business model innovation, digitalization, Industry 4.0, digital platforms and e-commerce, people and digital transformation and digital institutional environment.Originality/valueIn recent years, the term digital transformation has become part of the daily lives of many organizations and of life in society itself. For internationalized companies, this discussion has also become present. Although a relationship between digital transformation and internationalization is often presented, the dimensions of analysis of this relationship are still very fragmented, and this study presents a systemic view of the themes. These themes represent opportunities for future studies.