Early Administration of Hypertonic-Hyperoncotic Hydroxyethyl Starch (HyperHES) Improves Cerebral Blood Flow and Outcome After Experimental Subarachnoid Hemorrhage in Rats

Lilla, Nadine; Rinne, Christoph; Weiland, Judith; Linsenmann, Thomas; Ernestus, Ralf‐Ingo; Westermaier, Thomas

doi:10.1016/j.wneu.2018.03.205

Cited by 5 publications

(1 citation statement)

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“…as expansion drugs, while the control group used conventional treatment or crystalloid. However, these clinical trials have not yet reached a satisfactory conclusion [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Volume Expansion Therapeutic Effect in Acute Ischemic Stroke

Liu

et al. 2019

J Neurol Res

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Background: Volume expansion therapy is widely used in clinical practice, whether expansion therapy has a certain effect on the recovery of neurological function in patients with ischemic stroke is very worth exploring. Our aim is to explore the value of dextran injection in patients with acute ischemic stroke. Methods:A total of 101 patients with cerebral infarction were divided into two groups: the expansion group and the control group. National Institutes of Health Stroke Scale (NIHSS) scores were assessed at the time of admission and discharge. Results:There was no statistically significant difference in neurological function improvement between the treatment group and the control group (P > 0.05). Moreover, some factors including age, sex, NIHSS baseline score, systolic blood pressure before treatment, hypertension, diabetes mellitus, coronary heart disease, degree of cerebral arterial stenosis and option of treatment method have no statistically significant contribution to the patients (P > 0.05). Conclusions:Dextran injection may not improve the degree of neurological deficit in acute ischemic stroke patients.

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“…as expansion drugs, while the control group used conventional treatment or crystalloid. However, these clinical trials have not yet reached a satisfactory conclusion [6][7][8].…”

Section: Introductionmentioning

confidence: 99%