Early bone ingrowth and segmental stability of a trussed titanium cage versus a polyether ether ketone cage in an ovine lumbar interbody fusion model

Loenen, Arjan C Y; Peters, M.; Bevers, Raymond; Schaffrath, C; Haver, Els van; Cuijpers, Vincent M.J.I.; Rademakers, Timo; Rietbergen, Bert van; Willems, Paul; Arts, Jacobus J.

doi:10.1016/j.spinee.2021.07.011

Cited by 14 publications

(11 citation statements)

References 39 publications

(30 reference statements)

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“…Although the sheep model is frequently used in the study of spinal devices [36,37], the use of sheep to assess the therapeutic value of spinal devices should first be discussed from a biomechanical perspective. The largest difference between bipeds and sheep, which are quadrupeds, is the direction of the spine axis, which is vertical in humans and horizontal in sheep.…”

Section: Validation Of the Sheep Model To Ensure Clinical Relevancementioning

confidence: 99%

Outstanding in vivo mechanical integrity of additively manufactured spinal cages with a novel “honeycomb tree structure” design via guiding bone matrix orientation

Ishimoto¹,

Kobayashi²,

Takahata³

et al. 2022

The Spine Journal

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Section: Validation Of the Sheep Model To Ensure Clinical Relevancementioning

confidence: 99%

Outstanding in vivo mechanical integrity of additively manufactured spinal cages with a novel “honeycomb tree structure” design via guiding bone matrix orientation

Ishimoto¹,

Kobayashi²,

Takahata³

et al. 2022

The Spine Journal

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“…While titanium confines give quick stability and endure critical compressive powers, PEEK confines have the advantage of a modulus of flexibility similar to cortical bone [33]. Although, there are no distinctions from those operated with recently developed TT cages regarding segmental stability it showed an alternate technique of bone ingrowth and attachment [34].…”

Section: Bone Graft and Cage Materialsmentioning

confidence: 99%

An Overview in the Management of Lumbar Degenerative Disc Diseases: Review Article

Albaker

Younis

Hafiz

et al. 2021

JPRI

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The degenerative disease of the intervertebral disc and back pain are chronic conditions that are caused by several factors and represent an important cause of morbidity and mortality in everyday clinical practice. The study aims to summarize the updated evidence regards epidemiology, pathophysiology, clinical manifestation, diagnosis, and management of degenerative disc diseases. The incidence of low back pain, which is the main symptom in Intervertebral Disc (IVD) disease, varies widely among different reports. It is the fifth most common cause for the visit to the doctor and affects 7.6 to 37% of patients. IVD degeneration is attributed to a complex interplay between environmental and genetic factors. DDD is a process that includes a progressive decrease in disk nutrient supply and changes in extracellular matrix (ECM) composition, which weakens the tissue strength and alters the cell metabolism.Degenerative lumb disc disease patients typically present with mechanical lower back pain, which is worse on forward flexion and when carrying heavy load. The pain is relieved with rest. Diagnosis of DDD is done by various methods, computed tomography (CT) scan, magnetic resonance imaging (MRI), and provocative discography. These methods should be used in conjunction with the patient history, physical examination and specific biomarker to monitor the response to treatment. There are three major lines of management of DDD; Treatment Options for Relief of Pain in Conservative Therapy.Treatment with Aims of Restoration, Repair, and Regeneration of Intervertebral Disc Diseases: Molecular Therapy. Reconstructive Strategies: Percutaneous Intervertebral Disc Techniques. Definitive Treatment for Intervertebral Disc Diseases :( surgical management).

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“…The isolated intervertebral segments were processed for undecalcified histology as described before [17]. In short, specimens were fixed in formalin, dehydrated through a series of ethanol, and polymerized with methyl methacrylate.…”

Section: Histologymentioning

confidence: 99%

Local bone metabolism during the consolidation process of spinal interbody fusion

et al. 2021

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Early bone ingrowth and segmental stability of a trussed titanium cage versus a polyether ether ketone cage in an ovine lumbar interbody fusion model

Abstract: Early bone ingrowth and segmental stability of a trussed titanium cage versus a polyether ether ketone cage in an ovine lumbar interbody fusion model,

Cited by 14 publications

References 39 publications

Outstanding in vivo mechanical integrity of additively manufactured spinal cages with a novel “honeycomb tree structure” design via guiding bone matrix orientation

Outstanding in vivo mechanical integrity of additively manufactured spinal cages with a novel “honeycomb tree structure” design via guiding bone matrix orientation

An Overview in the Management of Lumbar Degenerative Disc Diseases: Review Article

Local bone metabolism during the consolidation process of spinal interbody fusion

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