Early developmental exposure to pentachlorophenol causes alterations on mRNA expressions of caspase protease family in zebrafish embryos

Zhao, Jing; Huang, Gaofeng; Xu, Ting; Yin, Daqiang; Bai, Jianfeng; Gu, Weihua

doi:10.1016/j.chemosphere.2017.03.100

Cited by 7 publications

(1 citation statement)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Caspases, a family of cysteine proteases, are involved in several biological processes, such as inflammation and apoptosis (Nakajima et al, 2000; Zhao et al, 2017). They all contain a main domain, the carboxyl‐terminal catalytic domain (CASc).…”

Section: Introductionmentioning

confidence: 99%

Genome‐wide characterization of caspase genes in Japanese pufferfish, Takifugu rubripes, and expression profiles in response to Vibrio harveyi infection

Yang

Liu

Yang

et al. 2022

J World Aquaculture Soc

View full text Add to dashboard Cite

Caspases, also known as cysteine-dependent aspartatedirected proteases, play an important role in regulating apoptosis during development and inflammation. In this study, 10 caspase genes were characterized by searching the Japanese pufferfish genome using various bioinformatics methods, such as multiple sequence alignment and phylogenetic analysis. Additionally, we characterized the caspase genes and examined the expression profiles of every member in both healthy tissues and tissues infected with Vibrio harveyi in the liver and intestine. Our results revealed that 10 caspase genes were detected in all examined tissues, and the expression levels varied among different tissues and genes. Vibrio harveyi infection induced significant changes in the expression of 10 caspases in a time-dependent manner, suggesting that they might play

show abstract

Section: Introductionmentioning

confidence: 99%