Early Implementation of Palliative and Supportive Care in Hepatocellular Carcinoma

Gofton, Cameron; Agar, Meera; George, Jacob

doi:10.1055/a-1946-5592

Cited by 5 publications

(1 citation statement)

References 135 publications

(393 reference statements)

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“…This model of care has been shown to increase survival, decrease hospitalizations, and improve patient QOL [100]. There are currently limited evidence-based data to provide recommendations regarding PC involvement specifically in HCC care [101]. Further research is needed to better understand the timing of PC referral, intervention, and outcomes of HCC patients receiving PC.…”

Section: Best Supportive Care: Incorporation Of Non-hospice Palliativ...mentioning

confidence: 99%

Management of Hepatocellular Carcinoma in 2024: The Multidisciplinary Paradigm in an Evolving Treatment Landscape

Kinsey,

Lee

2024

Cancers

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Liver cancer is the third most common cause of cancer-related deaths worldwide, and hepatocellular carcinoma (HCC) makes up the majority of liver cancer cases. Despite the stabilization of incidence rates in recent years due to effective viral hepatitis treatments, as well as improved outcomes from early detection and treatment advances, the burden of HCC is anticipated to rise again due to increasing rates of metabolic dysfunction-associated steatotic liver disease and alcohol-related liver disease. The treatment landscape is evolving and requires a multidisciplinary approach, often involving multi-modal treatments that include surgical resection, transplantation, local regional therapies, and systemic treatments. The optimal approach to the care of the HCC patient requires a multidisciplinary team involving hepatology, medical oncology, diagnostic and interventional radiology, radiation oncology, and surgery. In order to determine which approach is best, an individualized treatment plan should consider the patient’s liver function, functional status, comorbidities, cancer stage, and preferences. In this review, we provide an overview of the current treatment options and key trials that have revolutionized the management of HCC. We also discuss evolving treatment paradigms for the future.

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Section: Best Supportive Care: Incorporation Of Non-hospice Palliativ...mentioning

confidence: 99%

Management of Hepatocellular Carcinoma in 2024: The Multidisciplinary Paradigm in an Evolving Treatment Landscape

Kinsey,

Lee

2024

Cancers

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Navigating Cirrhosis: Presentation, Outcomes, and Treatments in Adulthood and Beyond

Tahir,

Verma,

Siraj

et al. 2024

Curr Treat Options Gastro

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Exploring patient awareness of palliative care - optimal timing and preferred approaches

Trevizan,

Paiva,

de Almeida

et al. 2024

Pall Supp Care

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Objectives To explore patients’ awareness levels of palliative care (PC) and how this awareness shapes their preferences regarding the timing and approach for discussing it. Methods The study, conducted at a prominent institution specializing in oncology care, enrolled women aged 18–75 years who had been diagnosed with breast cancer. Patients completed guiding questions: Do you know what PC is?, When is the most appropriate time and the most appropriate way to discuss PC?. The interviews were conducted exclusively via video call and were recorded, transcribed, and then deleted. Results The study involved 61 participants, averaging 49 years old. Almost half (47.5%) had completed high school. Qualitative data analysis revealed 9 thematic categories. Regarding the first question, 2 divergent categories emerged: care for life and threatening treatment. For the second question, opinions diverged into 4 categories: At an early stage, mid-course of the disease, as late as possible, and no time at all. For the third question, 3 categories emerged: communication and support, care setting and environment, and improving the PC experience. Significance of Results This study reveals diverse perspectives on patients’ awareness and preferences for discussing PC, challenging the misconception that it’s only for end-of-life (EOL) situations. Comprehending PC influences when and how patients discuss it. If tied solely to EOL scenarios, discussions may be delayed. Conversely, understanding its role in enhancing advance support encourages earlier conversations. Limited awareness might delay talks, while informed patients actively contribute to shared decision-making. Some patients prefered early involvement, others find mid-treatment discussions stress-relieving. Community support, quiet environments, and accessible resources, underscoring the importance of a calm, empathetic approach, emphasizing the importance of understanding its role in advance support and providing valuable implications for enhancing patient care practices, theories, and policies.

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Early Implementation of Palliative and Supportive Care in Hepatocellular Carcinoma

Cited by 5 publications

References 135 publications

Management of Hepatocellular Carcinoma in 2024: The Multidisciplinary Paradigm in an Evolving Treatment Landscape

Management of Hepatocellular Carcinoma in 2024: The Multidisciplinary Paradigm in an Evolving Treatment Landscape

Navigating Cirrhosis: Presentation, Outcomes, and Treatments in Adulthood and Beyond

Exploring patient awareness of palliative care - optimal timing and preferred approaches

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