Early Loading after 21 Days of Healing of Nonsubmerged Titanium Implants with a Chemically Modified Sandblasted and Acid‐Etched Surface: Two‐Year Results of a Prospective Two‐Center Study

Abstract

The results of this prospective two-center study demonstrate that titanium implants with a modified SLA surface can predictably achieve successful tissue integration when loaded in full occlusion 21 days after placement. Integration could be maintained without incident for at least 2 years of follow-up.

Bilateral sinus floor augmentation using 100% alloplastic biomaterial for later rehabilitation of atrophic maxilla. A 5-year tomographic follow-up

“…30 Experimental trials report significant bone apposition and anchorage to implant surfaces at the initial stages of bone repair in animal models. 29 These experimental outcomes were confirmed not only by prospective clinical studies in which implants were loaded after 21 days of bone repair, 33,34 but also by studies measuring implant stability with the aid of resonance frequency analysis (RFA), 35 genetic expression profile and histological analysis of human models. 36,37 As regards the use of antibiotics, a recent systematic review concluded that scientific evidence suggests that, in general, this type of drug is advantageous, as it aids reducing failure rates of implants placed under normal conditions.…”

The role of a moderately rough and chemically modified implant surface in an early loading protocol: a literature review

“…In the study by Bornstein et al, 35 all 56 implants, including the two "spinners", successfully integrated, presenting favorable clinical and radiographic conditions resulting in a 3-year survival and success rate of 100% (Figs 4, 5). In the study by Morton et al, 36 the overall success rate after a 2-year follow-up was 97.7%.…”

“…37 The different times for loading dental implants have been somewhat confusing in the past; however, in accordance with recently published reports, the early loading protocol is adopted when prosthesis is connected to the dental implants between 1 and 8 weeks following implant placement. 50,51 Prospective clinical studies with up to three years of follow-up 35,36 demonstrated favorable results for implants with a MRCM surface when loaded after 21 days of bone repair using an early loading protocol under well-defined clinical conditions without bone defects. Thus, implants with a MRCM surface loaded after three weeks of bone repair achieved a similar outcome to that reported for implants with a standard MR surface using an early loading protocol after 6 to 8 weeks.…”

Osseointegration and Bioscience of Implant Surfaces - Current Concepts at Bone-Implant Interface

“…Over the past two decades, elevating the local quality and quantity of the host tissue for an optimal osseointegration was the major goal of implant dentistry in order to overcome these drawbacks. Therefore, various approaches have focused on finding alternative methods to accelerate and optimize osseointegration, aiming at sufficient mechanical integrity to withstand occlusal forces at an early period (Morton et al, 2010). During the first 10-20 years of understanding the healing mechanisms of traumatized bone where implants are placed, the concept that successful osseointegration was the result of titanium implant biocompatibility dominated clinical thinking.…”