Early Outcomes With Marginal Donor Hearts Compared With Left Ventricular Assist Device Support in Patients With Advanced Heart Failure

Optimal timing for heart transplantation in patients bridged with left ventricular assist devices: Is timing of the essence?

“…Among these patients who are selected for transplantation, recent evidence with continuous flow devices suggests no differences in mortality compared with patients that go directly to HTx. [7][8][9][10] However, very few studies have investigated the influence on the duration of BTT with an LVAD on posttransplant outcomes. The 2 most recent studies demonstrated no survival difference based on the duration of BTT with a LVAD, yet these reports were either limited to short follow-up times or conducted as a small, singlecenter experience.…”

The Paradoxical Relationship Between Donor Distance and Survival After Heart Transplantation

“…Marginal donors have been recognized as one avenue to expand the donor pool [13,14]. Despite the potential to further shorten wait list time and potentially decrease wait list mortality, marginal donors pose significant risk to successful transplantation [15]. Previous literature has identified donor age older than 40 years and donor female sex as risk factors for 1-year mortality [16].…”

Heart Transplantation After Ventricular Assist Device Therapy: Benefits, Risks, and Outcomes

“…CF-LVAD recipients with higher age, body mass index (BMI), and creatinine had an increased graft failure risk. Schumer et al 15 in their study tried to address the same concerns regarding MDs in a slightly different manner. They compared wait-list survival of BTT LVAD patients to post-OHT survival of MD recipients.…”