Early recovery from alcohol dependence: Factors that promote or impede abstinence

Charney, Dara A.; Zikos, Eugenia; Gill, Kathryn

doi:10.1016/j.jsat.2009.06.002

Cited by 118 publications

(86 citation statements)

References 60 publications

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“…However, it is worth highlighting that the first weeks of abstinence are crucial in the management of alcohol-dependent patients, considering that craving is high, the presence of postdetoxification anhedonia is considerable, 46,47 and the possibility of relapse is concrete. 48 The results of this study need to be interpreted with caution due to these limitations. Although we did not test for efficacy in different subpopulations of alcoholic patients, we believe that specific subpopulations of alcohol abusers, such as Cloninger type II alcoholic patients 49 and subjects with specific typologies of craving, 50 could benefit from TOP in terms of efficacy, given the specific pharmacodynamics properties of this drug.…”

Section: Discussionmentioning

confidence: 84%

Low-Dose Topiramate in Alcohol Dependence

Martinotti¹,

Nicola²,

Vita³

et al. 2014

Journal of Clinical Psychopharmacology

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Section: Discussionmentioning

confidence: 84%

Low-Dose Topiramate in Alcohol Dependence

Martinotti¹,

Nicola²,

Vita³

et al. 2014

Journal of Clinical Psychopharmacology

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“…The literature on the link between impulsivity and addiction treatment outcomes clearly covers many other aspects than those discussed in the present paper, including personality aspects such as novelty and sensation seeking (Helstrom, Hutchison, & Bryan, 2007;Kahler et al, 2009;Patkar et al, 2004), attentional impulsivity (Charney, Zikos, & Gill, 2010) or lack of perseverance (Müller, Weijers, Böning, & Wiesbeck, 2008). These personality traits are typically assessed using self-report questionnaires, which may be less sensitive in identifying differences associated with treatment outcomes compared to neurocognitive tasks detailing specific behavioral processes.…”

Section: Limitations Of the Reviewmentioning

confidence: 99%

Impulsivity as a vulnerability factor for poor addiction treatment outcomes: A review of neurocognitive findings among individuals with substance use disorders

Stevens

Verdejo-García

Goudriaan

et al. 2014

Journal of Substance Abuse Treatment

274

178

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With the current review, we explore the hypothesis that individual differences in neurocognitive aspects of impulsivity (i.e., cognitive and motor disinhibition, delay discounting and impulsive decision-making) among individuals with a substance use disorder are linked to unfavorable addiction treatment outcomes, including high drop-out rates and difficulties in achieving and maintaining abstinence. A systematic review of the literature was carried out using PubMed, PsycINFO and Web of Knowledge searches. Twenty-five unique empirical papers were identified and findings were considered in relation to the different impulsivity dimensions. Although conceptual/methodological heterogeneity and lack of replication are key limitations of studies in this area, findings speak for a prominent role of cognitive disinhibition, delay discounting and impulsive decision-making in the ability to successfully achieve and maintain abstinence during and following addiction treatment. In contrast, indices of motor disinhibition appear to be unrelated to abstinence levels. Whereas the relationship between impulsivity and treatment retention needs to be examined more extensively, preliminary evidence suggests that impulsive/risky decision-making is unrelated to premature treatment drop-out among individuals with a substance use disorder. The reviewed findings are discussed in terms of their clinical implications.

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“…A handful of studies have indicated that the BIS score, particularly the cognitive component (Charney et al, 2010), can predict drinking outcomes at 4 weeks (Charney et al, 2010) and 12 months (Evren et al, 2012) in AUD. Moreover, slower SSRTs in heavy drinkers significantly predict alcohol consumption at 4 years follow-up, and the risk of development of AUD, whereas errors of omission on the CPT and BIS scores are also predictive in the expected direction, but non-significant (Rubio et al, 2008).…”

Section: Clinical Significance Of Deficits In Cognitive Controlmentioning

confidence: 99%