Easy Access to Water-Soluble Fullerene Derivatives via 1,3-Dipolar Cycloadditions of Azomethine Ylides to C₆₀

[60]Fullerene Amino Acids and Related Derivatives

“…Anti-HIV-1 protease (HIV-P) activities were also conducted on compound (9). From studies Although the mode of action of water-soluble [60]fullerene derivatives such as (74) have been hotly debated in the literature, they have shown a potential use for photodynamic therapy [76][77][78] .…”

“…[60]Fullerene derivatives exhibit a range of interesting biological activities including inhibition of HIV enzymes [4][5][6][7][8][9][10][11][12] , photoinduced cytotoxicity via selective cleavage of DNA [13][14][15][16][17] and as a smooth muscle relaxant [18][19][20] . In addition, other interesting reports of fullerene derivatives of biologically significant molecules such as lipids 21 , saccharides 22 , oligonucleotides [23][24] and amino acids have appeared in the literature.…”

Synthesis and Optical-Limiting Behavior of Hybrid Inorganic-Organic Materials from the Sol-Gel Processing of Organofullerenes

“…Scheme 3. To improve further the solubility of the fullerene derivatives, N-substituted glycine 11 [50,51] was condensed with aldehyde 7 in the presence of C 60 , which afforded fulleropyrrolidine 4 (Scheme 3).…”

“…Tetrahydrofuran, employed for UV/Vis measurements and sol ± gel film preparation, was distilled prior to use. N-(3,6,9-Trioxadecyl)glycine (11), [51] N-[3-(triethoxysilyl)propyl]-2-carbomethoxy-3,4-fulleropyrrolidine (5), [50] N-methyl-2-(3,6,9-trioxadecyl)-3,4-fulleropyrrolidine (12), [29] and N-methyl-2-(4-hydroxyphenyl)-3,4-fulleropyrrolidine [29] (13) were prepared as previously described.…”

Fullerenes: Synthesis and Applications

“…Irrespective of their extreme conjugation fullerenes behave as electron-deficient alkenes (Da Ros, Prato, Novello, Maggini, & Banfi, 1996) because they add nucleophiles, homolytic reagents and even free radicals to produce stable adducts .…”