Easy to Use Plastic Optical Fiber-Based Biosensor for Detection of Butanal

Cennamo, Nunzio; Giovanni, Stefano Di; Varriale, Antonio; Staiano, Maria; Pietrantonio, F. Di; Notargiacomo, A.; Zeni, Luigi; D’Auria, Sabato

doi:10.1371/journal.pone.0116770

Cited by 25 publications

(19 citation statements)

References 20 publications

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“…In this work, a new synthetic receptor, specifically designed to recognise C4 to C12 PFAs, is used with the same SPR-POF platform reaching a better LOD (130 ppt). This result could be considered of interest when compared to the detection limit of PFAs obtained by using different approaches, as reported in Oughena et al [ 25 ] and Trojanowicz et al [ 26 ] or Cennamo et al [ 27 ].…”

Section: Introductionmentioning

confidence: 71%

A Molecularly Imprinted Polymer on a Plasmonic Plastic Optical Fiber to Detect Perfluorinated Compounds in Water

Cennamo

D’Agostino²,

Porto³

et al. 2018

Sensors

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A novel Molecularly Imprinted Polymer (MIP) able to bind perfluorinated compounds, combined with a surface plasmon resonance (SPR) optical fiber platform, is presented. The new MIP receptor has been deposited on a D-shaped plastic optical fiber (POF) covered with a photoresist buffer layer and a thin gold film. The experimental results have shown that the developed SPR-POF-MIP sensor makes it possible to selectively detect the above compounds. In this work, we present the results obtained with perfluorooctanoate (PFOA) compound, and they hold true when obtained with a perfluorinated alkylated substances (PFAs) mixture sample. The sensor’s response is the same for PFOA, perfluorooctanesulfonate (PFOS) or PFA contaminants in the C4–C11 range. We have also tested a sensor based on a non-imprinted polymer (NIP) on the same SPR in a D-shaped POF platform. The limit of detection (LOD) of the developed chemical sensor was 0.13 ppb. It is similar to the one obtained by the configuration based on a specific antibody for PFOA/PFOS exploiting the same SPR-POF platform, already reported in literature. The advantage of an MIP receptor is that it presents a better stability out of the native environment, very good reproducibility, low cost and, furthermore, it can be directly deposited on the gold layer, without modifying the metal surface by functionalizing procedures.

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Section: Introductionmentioning

confidence: 71%

A Molecularly Imprinted Polymer on a Plasmonic Plastic Optical Fiber to Detect Perfluorinated Compounds in Water

Cennamo

D’Agostino²,

Porto³

et al. 2018

Sensors

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“…Furthermore, the DAS system based on surface plasmon resonance (SPR) are very sensitive to small changes in refractive index of external media [126]. Therefore, oil spill alarm products based on SPR sensing technology can realize real-time detection of oil spill process [127], and the cost is low [128]. Therefore, SPR sensing technology has been widely used in the measurement and detection of related physical quantities, which will cause the change of refractive index [129].…”

Section: Petroleum Exploration and Developmentmentioning

confidence: 99%

A Comprehensive Study of Optical Fiber Acoustic Sensing

et al. 2019

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The optical fiber acoustic sensing system is suitable for long-distance monitoring of the acoustic signals generated by the external disturbances. According to the continuity of sensing units, quasi-distributed and distributed optical fiber acoustic sensing technologies are differentiated to meet different application requirements. On the one hand, the recent progress of Fabry-Perot interferometer (FPI) focusing on the diaphragm material, and the research hotspots in the field of the continuous Fiber Bragg grating (FBG) array are firstly reviewed. On the other hand, Mach-Zehnder interferometry (MZI), Michelson interferometry (MI), and Sagnac interferometry (SI) have rapidly developed in the aspect of the demodulation algorithm optimization with the purpose of the sensing performance improvement. Moreover, the current primary research works of the phase-sensitive optical time-domain reflectometer (ϕ-OTDR) are the signalto-noise ratio improvement and the mixed optical structure design. Finally, this paper presents an overview of the recent advances of optical fiber acoustic sensing system in the application domains of military defense, structural health monitoring, petroleum exploration, and development. INDEX TERMS Acoustic detection, distributed acoustic sensing, optical fiber sensing, ϕ-OTDR, structural health monitoring.

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“…Moreover, it provides reliable results when the ligand is a large molecule, such as a protein or DNA fragment, but is not very accurate in the case of a small organic compounds, as an odorant. A simplified system has been described, with an OBP immobilised on an optical fibre, that could lead to the fabrication of portable biosensors [90].…”

Section: Transducing Strategiesmentioning

confidence: 99%

From Gas Sensors to Biomimetic Artificial Noses

2018

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Since the first attempts to mimic the human nose with artificial devices, a variety of sensors have been developed, ranging from simple inorganic and organic gas detectors to biosensing elements incorporating proteins of the biological olfactory system. In order to design a device able to mimic the human nose, two major issues still need to be addressed regarding the complexity of olfactory coding and the extreme sensitivity of the biological system. So far, only 50 of the approximately 300-400 functioning olfactory receptors have been de-orphanized, still a long way from breaking the human olfactory code. On the other hand, the exceptional sensitivity of the human nose is based on amplification mechanisms difficult to reproduce with electronic circuits, and perhaps novel approaches are required to address this issue. Here, we review the recent literature on chemical sensing both in biological systems and artificial devices, and try to establish the state-of-the-art towards the design of an electronic nose.

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Easy to Use Plastic Optical Fiber-Based Biosensor for Detection of Butanal

Cited by 25 publications

References 20 publications

A Molecularly Imprinted Polymer on a Plasmonic Plastic Optical Fiber to Detect Perfluorinated Compounds in Water

A Molecularly Imprinted Polymer on a Plasmonic Plastic Optical Fiber to Detect Perfluorinated Compounds in Water

A Comprehensive Study of Optical Fiber Acoustic Sensing

From Gas Sensors to Biomimetic Artificial Noses

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