Eating behavior in laparoscopic sleeve gastrectomy: Correlation between plasma ghrelin levels and hunger

Sleeve Gastrectomy as Sole and Definitive Bariatric Procedure: 5-Year Results for Weight Loss and Ghrelin

“…3 Plasma ghrelin levels following sleeve gastrectomy. Ghrelin levels decreased significantly after the procedure (p<0.05) and remained stable in non-converted patients for the duration of the follow-up We found a significant reduction of the plasma ghrelin levels [11] and a correlation between plasma ghrelin levels and the sensation of hunger in the short-term follow-up following SG [12]. The reduction of ghrelin levels after SG was also confirmed by two studies of Cohen et al [33] and Karamanakos et al [34].…”

“…As an appetite-inducing peptide hormone mainly deriving from the gastric fundus resected in SG, reduced plasma levels were found at 6 months after sleeve gastrectomy [11]. This might partially explain the reduced sensation of appetite of SG patients in the early postoperative period [12], supporting weight loss. However, a compensatory increase of plasma ghrelin levels in the longer follow-up might contribute to weight regain and, thus, limit the success of SG in the longer follow-up.…”

Laparoscopic Sleeve Gastrectomy, 529 Cases Without a Leak: Short-Term Results and Technical Considerations

“…In addition, there is continued disagreement as to whether LSG represents a strictly restrictive procedure versus a combination restrictive/hormonal procedure [11]. Studies have shown the effects of LSG on ghrelin levels and hunger [12], as well as additional metabolic hormones [13].…”

Conversion from Sleeve Gastrectomy to Roux-en-Y Gastric Bypass—Indications and Outcome

“…Nowadays, many bariatric centers perform SG as sole and definitive bariatric procedure not only in these selected patients but also in the morbidly obese with average operative risk. Weight loss was described by %EWL of approximately 60% for the first 2 years following SG [4,5,[29][30][31][32], which might partly be explained by the reduction of plasma ghrelin levels [23,33,34], contributing to the reduction in the sensation of hunger [31,34,35].…”