2004
DOI: 10.1038/sj.bjc.6601918
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Eating garlic and onion: a matter of life or death

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Cited by 18 publications
(13 citation statements)
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“…Niether was there granulation tissue formation. This is confirmed by other studies that speculate that Allium sativum has no negative effect on the prosta but rather might be beneficial in the management of prostate cancer (Izzo et al, 2004). …”
Section: Discussionsupporting
confidence: 84%
“…Niether was there granulation tissue formation. This is confirmed by other studies that speculate that Allium sativum has no negative effect on the prosta but rather might be beneficial in the management of prostate cancer (Izzo et al, 2004). …”
Section: Discussionsupporting
confidence: 84%
“…However, the mechanisms underlying the anticancer effects of this class of compounds are not fully understood. Several mechanisms have been proposed, including antioxidant activity, tumor growth inhibition, effective stimulation of the immune response, and induction of apoptosis, which coincides with an increase in the percentage of cells blocked in the G2/M phase of the cell cycle [31].…”
Section: Allium Compoundsmentioning
confidence: 99%
“…However the group that received 156 mg/kg of the extract also showed evidences of karyorrhexis. This is the fragmentation of the nucleus 22 . This result is similar to a previous report 12 .…”
Section: Discussionmentioning
confidence: 99%
“…This result is similar to a previous report 12 . Several investigations have shown that Allium sativum has deleterious effects on the cellular arrangement of various body parts including the prefrontal cortex, liver, kidney and heart 9,12 , as well as changes in the intestinal flora 7 , and induction of cell apoptosis 22 . However, it has also been reported that garlic prevents degeneration of the brain's frontal lobe and neuronal death in the hippocampus 3,4 , which may not be the case in the present study.…”
Section: Discussionmentioning
confidence: 99%