EBV and CMV in chronic periodontitis: a prevalence study

Chalabi, Maryam; Moghim, Sharareh; Mogharehabed, Ahmad; Najafi, Farid; Rezaie, Faranak

doi:10.1007/s00705-008-0186-7

Cited by 33 publications

(36 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a few studies, EBV is detected in a healthy oral cavity which is similar to our findings, but with no HCMV detection. 7,18,19 Although few studies showed similar detection rates of HCMV as in our study, there has been a wide and varied report with high levels of viruses to none in certain population with healthy periodontium. 7,9,17,18,[20][21][22][23] In CP, there have been varied reports with some studies finding very high levels of EBV and HCMV.…”

Section: Discussionsupporting

confidence: 79%

“…7,18,19 Although few studies showed similar detection rates of HCMV as in our study, there has been a wide and varied report with high levels of viruses to none in certain population with healthy periodontium. 7,9,17,18,[20][21][22][23] In CP, there have been varied reports with some studies finding very high levels of EBV and HCMV. 10,18,20,21,23 Our results showed significantly higher levels of both the HCMV and the EBV virus in CP as compared to the healthy periodontium but still was lower than the median range as quoted by Slots 2010.…”

Section: Discussionsupporting

confidence: 79%

“…24 Chalabi et al showed the prevalence of EBV-1 and CMV in Iran patients was 78.3 and 59% respectively. 18 Similarly, Kubar et al found EBV and HCMV at 56% for both in periodontitis in their study. 25 In our study the prevalence of EBV and HCMV were 21 and 31% respectively in CP patients.…”

Section: A Study Done By Contreras Et Al In American Patientssupporting

confidence: 53%

“…7,9,17,18,[20][21][22][23] In CP, there have been varied reports with some studies finding very high levels of EBV and HCMV. 10,18,20,21,23 Our results showed significantly higher levels of both the HCMV and the EBV virus in CP as compared to the healthy periodontium but still was lower than the median range as quoted by Slots 2010. 2 In his study, we noted that a co-infection of HCMV and EBV existed in CP group and this relationship was significant.…”

Section: Discussionmentioning

confidence: 99%

“…The findings of the present study were at lower levels as compared to some studies done in other countries. 18,[20][21][22][23] This could also be because the detection levels may depend on the virus being in the active or latent stage. The primary infection of the host with herpesvirus is followed by a state of latency and reactivation.…”

Section: A Study Done By Contreras Et Al In American Patientsmentioning

confidence: 99%

See 4 more Smart Citations

Prevalence of Herpesvirus and Correlation with Clinical Parameters in Indian Subjects with Chronic Periodontitis

Joshi¹,

Bhat²,

Katti³

et al. 2015

The Journal of Contemporary Dental Practice

View full text Add to dashboard Cite

Objective: The identification of new uncultured species and viruses supports the possibility of combination of the herpesvirus-bacterial periodontal infection for periodontitis. The paucity of data and studies with larger sample size in Indian subjects provides an unclear picture of the presence of the herpesvirus in this population. Materials and methods:This was a cross-sectional study consisting of 100 each in the healthy group and chronic periodontitis (CP) group. The subgingival plaque was collected and polymerase chain reaction was performed post deoxyribonucleic acid (DNA) extraction by using specific primers for human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV). The data were analyzed using Fisher's exact test, Mann-Whitney U test and Spearman's coefficient correlation.Results: Human cytomegalovirus and EBV viruses were significantly higher in the CP group as compare to the healthy group. A higher percentage of those with CMV positive had EBV also positive (28.3%) compared to only 9.1% of CMV negative being EBV positive in the CP group. When both the healthy and CP group in total was compared, there was a significant correlation with all clinical parameters. Conclusion:Both the viruses dominated in disease as compared to health were similar to the earlier findings. The CP group had higher pocket depth and clinical attachment loss in the virus positive subjects. These findings could suggest that 91-9620127630, e-mail: drvinayakjoshi@gmail.com virus serves as a prelude to the disease and the combination of the two viruses could play a role in the pathogenesis. Prevalence of Herpesvirus and Correlation with Clinical

show abstract

Section: Discussionsupporting

confidence: 79%

Section: Discussionsupporting

confidence: 79%

Section: A Study Done By Contreras Et Al In American Patientssupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Section: A Study Done By Contreras Et Al In American Patientsmentioning

confidence: 99%

See 3 more Smart Citations

Prevalence of Herpesvirus and Correlation with Clinical Parameters in Indian Subjects with Chronic Periodontitis

Joshi¹,

Bhat²,

Katti³

et al. 2015

The Journal of Contemporary Dental Practice

View full text Add to dashboard Cite

show abstract

Periodontal Microbiology

Dumitrescu¹,

Ohara²

2010

Etiology and Pathogenesis of Periodontal Disease

View full text Add to dashboard Cite

The prevalence of human herpes viruses in the saliva of chronic periodontitis patients compared to oral health providers and healthy controls

et al. 2013

View full text Add to dashboard Cite

The causative agents in periodontal disease are periopathogenic bacteria; however, viruses have been implicated. The aim of this study was to examine the prevalence of different HHVs in the saliva of chronic periodontitis patients and to compare it to two groups of healthy controls. Three groups were included: chronic periodontitis patients (CP), periodontally healthy patients (NP) and oral health providers with a healthy periodontium (NPOHP). For each subject, 1 ml of unstimulated whole saliva was collected and mixed with 2 ml lysis buffer. HHVs assays were performed using real-time PCR. Fifteen percent of the subjects in the CP group tested positive for CMV compared to none in the NP and NPOHP groups (p = 0.04). Recurrent herpes was more frequent in females (51.7 %) than in males (33.3 %), and this was statistically significant (p = 0.038). The higher prevalence of CMV in the unstimulated saliva of CP patients suggests that CMV may play a role in the pathogenesis of chronic periodontitis.

show abstract

EBV and CMV in chronic periodontitis: a prevalence study

Cited by 33 publications

References 23 publications

Prevalence of Herpesvirus and Correlation with Clinical Parameters in Indian Subjects with Chronic Periodontitis

Prevalence of Herpesvirus and Correlation with Clinical Parameters in Indian Subjects with Chronic Periodontitis

Periodontal Microbiology

The prevalence of human herpes viruses in the saliva of chronic periodontitis patients compared to oral health providers and healthy controls

Contact Info

Product

Resources

About