Eccrine Nevus Affecting the Forearm of an 11‐Year‐Old Girl Successfully Controlled with Topical Glycopyrrolate

Dua, Janet; Grabczynska, Sophie

doi:10.1111/pde.12127

Cited by 16 publications

(10 citation statements)

References 5 publications

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“…Intralesional administration of botulinum toxin, which prevents the release of acetylcholine at the neuromuscular junction, is very effective in treating localised hyperhidrosis although requiring serial reinjections. Successful treatment with topical glycopyrrolate has also been reported 21. Due to the anatomic location in these two cases, endoscopic thoracic sympathectomy could be an additional option.…”

Section: Discussionmentioning

confidence: 81%

Two patients with localised hyperhidrosis of the hand based on functional and structural abnormalities of sweat glands

Kristiansen¹,

Lindahl

Pallesen

et al. 2018

BMJ Case Reports

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A 14-year-old girl and a 30-year-old woman presented with localised hyperhidrosis on the dorsal hand and wrist, respectively, provoked by different stimuli such as physical activity and minor trauma to the skin. The skin was seemingly normal in both patients where an iodine-starch test revealed a well-demarcated area of hyperhidrosis. Following histopathological examination, the diagnosis was unilateral localised hyperhidrosis in both cases; one with normal histology and one with a nevus sudoriferous. Both patients were successfully treated with botulinum toxin type A. The 30-year-old woman additionally used low-dose propantheline bromide periodically and experienced long-term remission on this therapy. Hyperhidrosis may embarrass and interfere with patients' school and careers, and it is therefore important to tailor an effective individual treatment.

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Section: Discussionmentioning

confidence: 81%

Two patients with localised hyperhidrosis of the hand based on functional and structural abnormalities of sweat glands

Kristiansen¹,

Lindahl

Pallesen

et al. 2018

BMJ Case Reports

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“…Other interesting cases include a 3-month-old male with a congenital midline scalp lesion [8], an 11-year-old female with a wide area of hyperhidrosis on the right arm [9], and a 14-month-old male with a slow growing asymptomatic hypopigmented patch on his back since 3 months of age [10]. A summary of known cases is presented in Table 1.…”

Section: Discussionmentioning

confidence: 99%

“…Different methods have been used including surgery [4], antidepressants, anticholinergics, botulinum toxin, iontophoresis, and Glycopyrrolate pad [9]. …”

Section: Discussionmentioning

confidence: 99%

Eccrine Nevus Presenting with Umbilical Discharge: A Case Report and Review of the Literature

Bidari‐Zerehpoosh

Sabeti

Arman

et al. 2017

Case Reports in Dermatological Medicine

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Eccrine nevus is a rare skin lesion with protean manifestations like hyperhidrosis, discolored nodules, papules, and so forth, which has been reported in various anatomic parts of the body including the forearm, leg, thigh, back, and coccyx. Our patient was a 26-year-old male, who presented with increasing colorless and odorless episodic umbilical discharge. First impression for the patient was an umbilical sinus and the patient underwent surgery. Histopathological study revealed the lesion to be an eccrine nevus of the umbilicus. This is the first case of eccrine nevus presenting with umbilical discharge. We recommend that eccrine nevus should be considered as a differential diagnosis for umbilical discharge.

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“…Hence, the main options are observation or surgical excision. If hyperhidrosis is affecting the patients quality of life, treatment with topical glycopyrrolate [3], systemic anticholinergic agents, iontophoresis, and intralesional botulinum toxin may be useful [4].…”

Section: Discussionmentioning

confidence: 99%

Congenital eccrine nevus on the neck

Zhang¹,

Yan

Xiao³

2014

Dermatology Online Journal

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Eccrine nevus (EN) is a very rare hamartoma of the skin and with varying clinical manifestations. Histologically, these neoplasms present as a proliferation of normally structured eccrine sweat glands in the dermis. There have been no more than 20 cases previously have been reported in the English literature. Herein we report a 25-year-old man with eccrine nevus on the neck. To our best knowledge, this is the first case that the lesion affecting the neck.

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Eccrine Nevus Affecting the Forearm of an 11‐Year‐Old Girl Successfully Controlled with Topical Glycopyrrolate

Cited by 16 publications

References 5 publications

Two patients with localised hyperhidrosis of the hand based on functional and structural abnormalities of sweat glands

Two patients with localised hyperhidrosis of the hand based on functional and structural abnormalities of sweat glands

Eccrine Nevus Presenting with Umbilical Discharge: A Case Report and Review of the Literature

Congenital eccrine nevus on the neck

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