Eccrine spiradenoma: a case report

Chedid, Rodolfo; Nagel, Janaina; Barreto, Taynara de Mattos; Plata, Glaura Tinoco; Dutra, Anna Luiza Bento; Azevedo, Thales Pereira de

doi:10.5935/scd1984-8773.201572387

Cited by 4 publications

(13 citation statements)

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“…Surgical excision is the gold standard in the management of eccrine spiradenoma with low rates of recurrence. [5][6][7][8] In this case, the tumor recurred after 18 months of follow-up. The recurrence may be elucidated by the multinodular nature of the lesion, suggesting the potential presence of residual nodules that remained unaddressed during surgical excision.…”

Section: Discussionmentioning

confidence: 99%

Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Habib,

Al‐janabi,

Ahmad

et al. 2023

Clinical Case Reports

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Key Clinical MessageSpiradenoma is a rare benign adnexal tumor arising from eccrine sweat glands. It presents as a painful bluish nodular lesion which occurs rarely over the arms. This case report adds to a case where a recurrent spiradenoma occurred over the arm. The majority of reported cases involve young adults, making our pediatric case particularly unusual. Early diagnosis through excisional biopsy is crucial for optimal management and prevention of recurrence or malignant transformation. Eccrine spiradenoma is an uncommon tumor that should be kept in mind in case of a patient with a painful nodule. More genetic studies are needed for the best understanding of this rare tumor entity.

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Section: Discussionmentioning

confidence: 99%

Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Habib,

Al‐janabi,

Ahmad

et al. 2023

Clinical Case Reports

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“…Histológicamente los cilindromas están compuestos por células basaloides, que encajan como un rompecabezas, rodeados por una membrana basal engrosada, con dos tipos de células, células epiteliales periféricas indiferenciadas en empalizada y células ductales cada vez más diferenciadas de ubicación central y núcleos grandes; el tricoepitelioma son tumores dérmicos, compuestos por nidos superficiales de células basaloides, con quistes llenos de queratina, estroma fibroso sin atipia nuclear significativa y el espiroadenoma es un tumor basófilo uninodular o multinodular bien circunscrito con dos tipos de células, unas ubicadas en el centro, grandes y pálidas y células basaloides oscuras y pequeñas en la periferia [9][10][11] .…”

Section: Discussionunclassified

Síndrome de Brooke-Spiegler: una infrecuente enfermedad a tener en cuenta en la práctica dermatológica.

Letona-García

Vasquez-Bonilla

Medina

et al. 2022

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El síndrome de Brooke-Spiegler (SBS) es una enfermedad autosómica dominante infrecuente, los pacientes con el SBS presentan mutaciones en el gen supresor tumoral CYLD, más frecuente en mujeres que hombres, entre la segunda y tercera década de la vida con una relación hombre:mujer de 1:6-9.6 y su incidencia exacta se desconoce. Clínicamente se presentan de manera simultánea cilindroma, tricoepiteliomas y espiroadenomas. Se presenta el caso de una paciente femenina de 64 años, quien consultó por aparición de masas en cabeza, tronco y las cuatro extremidades de 10 años de evolución, posteriormente aparecieron lesiones en cuero cabelludo, donde el crecimiento tuvo una evolución más lenta y que llegaron a ulcerarse; busca atención medica hasta que las lesiones iniciaron a ulcerarse, por lo cual fue referida al Hospital General San Juan de Dios de la Ciudad de Guatemala, al servicio de dermatología, donde se le realizó hematología completa, química sanguínea, tomografía computarizada de cráneo y biopsia incisional en sacabocados de 4 mm de piel de frente, mentón, región preauricular derecha y pierna derecha, el estudio histopatológico de las lesiones cutáneas en las regiones preauricular derecha y de frente reporto cilindroma, piel de mentón tricoepitelioma y piel de pierna derecha espiroadenoma. Con los hallazgos clínicos, estudios de imagen y hallazgos histopatológico se llega al diagnóstico de síndrome de Brooke-Spiegler. El tratamiento fue la prescripción cuidados de piel y derivación a cirugía plástica para tratamiento quirúrgico reconstructivo y seguimiento por la consulta externa de dermatología y cirugía plástica. La presencia de cilindromas, tricoepiteliomas y espiroadenomas hacen pensar en un síndrome de Brooke-Spiegler, que tienden a tener presentaciones muy sugestivas, como el tumor en turbante y desfiguración de la región de la cabeza. El abordaje es multidisciplinario, sin un tratamiento definitivo y seguimiento para evaluar las posibles conversiones a malignidad de las lesiones ulceradas. Palabras claves: Cilindroma, CYLD, Espiroadenoma, Histopatología.

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“…2 They usually present as typically small, discrete, well defined, and were found to be embedded in normal eccrine sweat glands.Research shows no age, gender or common site predilection. 3,4 These tumors are usually benign but the signs of malignancy include new onset of pain, color change of nodule, a rapid increase in size, increase in severity of tenderness or new onset of ulceration of a stable nodule. Once these become malignant, they usually metastasize to the lymph nodes, bones, lungs, brain and shows an aggressive clinical course.…”

Section: Discussionmentioning

confidence: 99%

“…3 With the etiology of the tumor being unknown from several studies, it frequently occurs along with other skin adnexal tumors such as trichoblastoma, trichoepithelioma, and cylindroma. 4 Ultrasonography can play an important role in the diagnosis of these tumors in knowing the morphological features like nature, size, depth and vascularity of the nodules and also their relationship with adjacent structures and vessels. 3 The definitive diagnosis of the tumor can be made from the study of the skin biopsy of the lesion [Fig 3,4] and also from the cytological study of the fine needle aspirate of the lesion.…”

Section: Discussionmentioning

confidence: 99%

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Eccrine Spiradenoma

Krishna¹,

Sarma²,

Babu³

2020

IJCMR

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Introduction: Eccrine spiradenoma is extremely rare adnexal tumor of the sweat gland, mainly affecting middle aged persons with equal incidence in males and females. It is frequently a benign tumor characterized as solitary, painful deep-seated dermal nodule with most common sites being the upper thorax and face. Case report: A 35 year old male presented with multiple, painful swellings over scalp,face,anterior chest and back since 6 months with loss of weight and appetite for 2 months. On examination, patient had a single cervical lymph node of size 1*1cm in the right posterior triangle of neck. Multiple tender subcutaneous, hard, nonmobile swellings present over several areas with largest(2*1cm) over anterior chest wall. Histopathologically diagnosed as Eccrine spiradenoma which revealed clusters and sheets of cells having mild pleomorphic round to ovoid bland nuclei with indistinct cytoplasmic borders, occasional duct or follicular appearance and empty looking lumina with no necrosis or mitotic activity. Conclusion: Eccrine spiradenoma, a rare benign adnexal tumor confirmed by histopathological examination. Differential diagnosis include, Neuroma, Dermatofibroma, Glomus tumor, Angiolipoma, Cylindromas and leiomyomas. Diagnosis confirmation by histopathological examination is crucial because of its potential for malignant transformation. Its prognosis is poor as it has multiple recurrences. Histopathological examination is gold standard for the diagnosis.

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Eccrine spiradenoma: a case report

Cited by 4 publications

References 5 publications

Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Síndrome de Brooke-Spiegler: una infrecuente enfermedad a tener en cuenta en la práctica dermatológica.

Eccrine Spiradenoma

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