Echocardiography and other imaging modalities in pulmonary arterial hypertension

Özben, Beste; Başaran, Yelda

doi:10.5152/akd.2010.116

Cited by 7 publications

(8 citation statements)

References 32 publications

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“…Studies suggest that severe OSA is independently associated with pulmonary hypertension in direct relationship with disease severity and application of CPAP reduces pulmonary systolic pressure levels (28). The E/Em ratio described as a predictor of left atrial pressure was also found to be reduced in our study however, the observed difference was not statistically significant.…”

Section: Discussioncontrasting

confidence: 56%

The effect of long term continuous positive airway pressure treatment on systolic and diastolic function in patients with obstructive sleep apnoea syndrome: A five year observational study

Bilge¹,

Yavuz²,

Çetin³

et al. 2014

Anadolu Kardiyol Derg

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Objective: Evaluation of the long-term effects of continuous positive airway presure (CPAP) on mean heart rate and left ventricular systolic and diastolic parameters in obstructive sleep apnea syndrome (OSAS) using conventional and tissue Doppler techniques. Methods: This prospective cohort study is designed to evaluate the long-term effects of CPAP treatments in normotensive OSAS patients. Initially 40 patients aged from eighteen to fifty five with documented OSAS syndrome were evaluated within one month of CPAP treatment. All had high self-reported compliance with treatment. From the latter, 21 patients with uninterrupted CPAP therapy (for at least 5 years, 5 hours per day) were included in the study and further evaluated with treatment. The left ventricular systolic function was assessed on apical four-chamber view using modified Simpson method and diastolic function was evaluated with classic transmitral pulsed and tissue Doppler techniques. Paired t test and Wilcoxon signed rank test had been used to compare the clinical and echocardiography data before and after treatment period. Results: A comparison of values assessed after one month and after 5 years of CPAP therapy, revealed a significant increase in the acceleration time(AT) Em/Am ratio and ejection time (ET) (AT: p=0.04; Em/Am ratio p=0.03 ET: p=0.04) while a significant decrease was observed on deceleration time (DT), isovolumetric relaxation time (IRT), myocardial performance index (MPI), mitral regurgitation (MR) and 24 hour mean heart rate (HR) in all subjects (DT: p=0.02; IVRT: p=0,04; MPI: p=0,01; MR: p≤0.001; HR: p=0.004). Conclusion: We observed a significant improvement in the left ventricular systolic and diastolic function and a significant decrease of 24-hour heart rate and mitral regurgitation with unchanged ejection fraction of the left ventricle with long-term CPAP treatment similar to short-term treatment studies. The long-term maintenance of the beneficial effect of CPAP throughout the 5 year long-term treatment can be one of the pathophysiologic mechanisms that may explain the decrease of cardiovascular mortality observed with long-term CPAP therapy in OSAS patients. (Anadolu Kardiyol Derg 2014; 14: 265-71)

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Section: Discussioncontrasting

confidence: 56%

The effect of long term continuous positive airway pressure treatment on systolic and diastolic function in patients with obstructive sleep apnoea syndrome: A five year observational study

Bilge¹,

Yavuz²,

Çetin³

et al. 2014

Anadolu Kardiyol Derg

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“…TAPSE reflects the right ventricle systolic function, whereas Tei shows both systolic and diastolic functions (31,32). In our study, TAPSE was found significantly different between groups, but the difference of Tei index was not significant.…”

Section: Discussionmentioning

confidence: 99%

Long-term prognosis of mild functional tricuspid regurgitation after mitral valve replacement: an observational retrospective study

Gürsoy¹,

Bakuy²,

Hatemi³

et al. 2013

Anadolu Kardiyol Derg

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Objective: Functional tricuspid regurgitation (FTR) is the most common type of tricuspid insufficiency and occurs approximately in 30% of patients with mitral valve disease. The major etiologic factor in the triggering of right ventricular dilation and thus causing functional tricuspid regurgitation, is pulmonary artery hypertension secondary to mitral valve disease. We aimed to analyze long-term outcomes of patients with mild tricuspid regurgitation at the time of mitral valve replacement. Methods: Sixty-six patients with mild tricuspid insufficiency who underwent mitral valve replacement were included in this observational retrospective study. Mean follow-up time was 8.3±0.7 years. Patients whose tricuspid regurgitation remained unchanged or decreased following operation were enrolled to group 1 (n=32), patients whose tricuspid regurgitation increased were included to group 2 (n=34) and data were compared statistically with t-test, Mann-Whitney U, Chi-square and Fisher Exact test. Multiple regression analysis was performed to determine independent risk factors for FTR progression. Results: Preoperatively female gender (p=0.02), body surface area (p=0.04), left atrium diameter (p=0.01), functional capacity (p=0.03), right ventricle diameter (p=0.04), and left ventricle mass index (p=0.04) were found to be statistically significant between groups. In the follow-up; functional capacity, grade of tricuspid insufficiency, pulmonary artery pressure, vena contracta width (p<0.001), TAPSE (tricuspid annular plane systolic excursion index) (p=0.04), annulus diameter (p=0.02), right ventricle diameter (p=0.01), left ventricle mass index (p=0.05), and ejection fraction (p=0.02) were found to be statistically different between groups. In multiple logistic regression analysis; preoperative LA diameter (OR=5.05; 95% CI:1.49-17.12; p=0.009) and female gender (OR=10.93; 95% CI:1.77-67.31; p=0.01) were found as independent risk factors for FTR progression. Conclusion: This study revealed that mild FTR might advance to moderate to severe grade in more than half of the patients in the follow-up. Thus, surgical approach to even mild FTR should be individualized based on patient's risk assessment. (Anadolu Kardiyol Derg 2014; 14: 34-9)

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“…Ekokardiyografik tekniklerden biri olan triküspit anüler plan sistolik hareket (TAPSH)'nin pulmoner hipertansiyonlu hastalarda prognostik önemi olduğu gösterilmiştir. [15] Normofonksiyone sağ ventrikülde, triküspit kapak anülüsü sistol esnasında apekse doğru 15-20 mm yaklaşır. Bu TAPSH'nin normal değeridir.…”

Section: Discussionunclassified

Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Sunar¹

2013

Turk Gogus Kalp Dama

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Background:This study aims to assess the early results of pulmonary endarterectomy. Methods: Between March 2011 and July 2012, 64 patients (29 males, 35 females; mean age 47.4±10.4 years; range 14 to 78 years) who underwent pulmonary endarterectomy were retrospectively analyzed. Preoperative and postoperative Doppler echocardiographic evaluation of pulmonary arterial hemodynamics and right ventricular function were evaluated. Variables were expressed in a mean ± standard deviation. The comparisons were made using independent sample t-test (p<0.05). A p value of <0.05 was considered significant. Results:The preoperative mean systolic pulmonary artery pressure was 75.4±25.5 mmHg, while the mean pulmonary vascular resistance was 801.7±449.5 dynes.sec.cm

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Echocardiography and other imaging modalities in pulmonary arterial hypertension

Cited by 7 publications

References 32 publications

The effect of long term continuous positive airway pressure treatment on systolic and diastolic function in patients with obstructive sleep apnoea syndrome: A five year observational study

The effect of long term continuous positive airway pressure treatment on systolic and diastolic function in patients with obstructive sleep apnoea syndrome: A five year observational study

Long-term prognosis of mild functional tricuspid regurgitation after mitral valve replacement: an observational retrospective study

Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

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