Ecological and functional implications of the acid-adaptation ability of Bifidobacterium: A way of selecting improved probiotic strains

Sanz, Yolanda

doi:10.1016/j.idairyj.2007.01.016

Cited by 77 publications

(51 citation statements)

References 41 publications

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“…Probiotics are defined as live microorganisms which upon ingestion in adequate numbers impart health benefits to the host animal beyond inherent basic nutrition [4,9,10]. Most of the probiotic species belong to the genera Lactobacillus and Bifidobacterium [11,12,13].…”

Section: Introductionmentioning

confidence: 99%

Cereal-Based Functional Foods

Nyanzi¹,

Jooste²

2012

Probiotics

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Section: Introductionmentioning

confidence: 99%

Cereal-Based Functional Foods

Nyanzi¹,

Jooste²

2012

Probiotics

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“…Bifidobacteria have beneficial effects in the prevention, and relieve of infectious diarrhea, and an improvement in the symptomatology of inflammatory bowel disease (110). Specific lineages of bifidobacteria suppress genes that are induced by H. pylori in human epithelial cells (111), while Bifidobacterium sp.…”

Section: Probiotics Therapeutic Applicationsmentioning

confidence: 99%

Probiotic: effectiveness nutrition in cancer treatment and prevention

et al. 2016

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Key words:Colorectal cancer. Infl ammatory bowel disease. Probiotics. Intestinal microbiota. Immune system. Palabras clave:Cáncer colorrectal. Enfermedad infl amatoria intestinal. Probióticos. Microbiota intestinal. Sistema inmune. ResumenEntre las neoplasias, el cáncer colorrectal es una de las principales causas de muerte por cáncer en hombres y mujeres. El aumento de la incidencia de este tipo de cáncer es debido al aumento de la esperanza de vida de la población y al aumento de las enfermedades infl amatorias crónicas del intestino, colitis ulcerosa y principalmente la enfermedad de Crohn, así como el cambio en los hábitos alimenticios. La American Cancer Society (2011) muestra que la dieta podría ser responsable de aproximadamente el 30% de los casos de cáncer en los países desarrollados; por otra parte, cuando se considera solo el cáncer colorrectal, el número puede ser del 30% al 50%. Los probióticos son efi caces en la prevención y el tratamiento de muchas enfermedades intestinales como la enfermedad infl amatoria del intestino (IBD), la diarrea, el síndrome del intestino irritable, la intolerancia al gluten, la gastroenteritis, la infección por Helicobacter pylori y el cáncer de colon. Ejemplos clásicos son cepas de los géneros Lactobacillus y Bifi dobacterium que tienen propiedades probióticas con un uso potencial en la profi laxis, así como en el tratamiento de una variedad de trastornos del tracto gastrointestinal. Los investigadores se están centrando en estudios muy importantes relacionados con la posibilidad de que el uso de probióticos pueda promover una composición de la microbiota equilibrada, y un sistema de vigilancia inmunológica sufi ciente como una forma de prevenir el cáncer. Teniendo en cuenta el hecho de que en los intestinos humanos viven 100 billones de bacterias, incluyendo más de 1.000 especies, todavía hay necesidad de realizar más investigaciones en profundidad con el fi n de encontrar probióticos con potencial para prevenir y tratar enfermedades cancerosas, añadiendo un efecto muy prometedor a este ya exitoso panorama. Esta revisión tiene como objetivo realizar una revisión de los estudios más recientes que relacionan los probióticos y su potencial con la prevención y el tratamiento del cáncer. AbstractAmong the neoplasias, colorectal cancer is one of the leading causes of cancer death in men and women. The increasing incidence of this type of cancer is due to the increase in the population's life expectancy, by the increase in chronic infl ammatory bowel diseases, primarily ulcerative colitis and Crohn's disease, and the change in eating habits. The American Cancer Society (2011) shows that diet might be responsible for approximately 30% of cancer cases in developed countries, moreover when considering only colorectal cancer, the number can reach 30% to 50%. Probiotics are effective in the prevention and treatment of many bowel diseases as infl ammatory bowel disease (IBD), diarrhea, irritable bowel syndrome, gluten intolerance, gastroenteritis, Helicobacter pylori infection, an...

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“…In general, bifidobacteria tolerance to acid is reduced with the exception of B. animalis [34,45]. Isolation of strains with good acid tolerance is desirable, since it is usually related to cross-resistance to some other stress factors, either those characteristic of the intestinal environment or typical of technological processes [13,79].…”

Section: Acid Phmentioning

confidence: 99%

How do bifidobacteria counteract environmental challenges? Mechanisms involved and physiological consequences

et al. 2011

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An effective response to stress is of paramount importance for probiotic bifidobacteria administered in foods, since it determines their performance as beneficial microorganisms. Firstly, bifidobacteria have to be resistant to the stress sources typical in manufacturing, including heating, exposure to low water activities, osmotic shock and presence of oxygen. Secondly, and once they are orally ingested, bifidobacteria have to overcome physiological barriers in order to arrive in the large intestine biologically active. These barriers are mainly the acid pH in the stomach and the presence of high bile salt concentrations in the small intestine. In addition, the large intestine is, in terms of microbial amounts, a densely populated environment in which there is an extreme variability in carbon source availability. For this reason, bifidobacteria harbours a wide molecular machinery allowing the degradation of a wide variety of otherwise non-digestible sugars. In this review, the molecular mechanisms allowing this bacterial group to favourably react to the presence of different stress sources are presented and discussed.

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Ecological and functional implications of the acid-adaptation ability of Bifidobacterium: A way of selecting improved probiotic strains

Cited by 77 publications

References 41 publications

Cereal-Based Functional Foods

Cereal-Based Functional Foods

Probiotic: effectiveness nutrition in cancer treatment and prevention

How do bifidobacteria counteract environmental challenges? Mechanisms involved and physiological consequences

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