Corn is one of the most important grains in the human food basket, which is also widely cultivated in Iran. This research was conducted with the aim of evaluating the status of arsenic, lead and chromium contamination in corn (Zea mays) samples grown in Dezful and Behbahan cities from Khuzestan province. In this research, 5 farms were randomly selected in each city and from each field, 5 soil samples and 5 corn samples were prepared in the summer season. For the autumn season, the same sampling was done as in the summer season. Therefore, a total of 50 soil samples and 50 corn samples were collected from the two study areas of Dezful and Behbahan cities in 2022. The average concentration of Pb, As and Cr in corn samples was 1.84, 1.57 and 4.92 mg kg− 1 and in soil samples 11.91, 4.02 and 76.86 mg kg− 1 respectively. The concentration of As and Cr in the soil of the agricultural fields of Dezful was higher in the fall season and in the corn samples in the summer season. The amount of Pb in corn and soil samples of agricultural fields in Behbahan was higher in autumn than in Dezful. According to the non-carcinogenic risk index (THQ) and carcinogenic risk index (CR), metals can be dangerous for human health, but the non-carcinogenic hazard index (THQ) for Cr does not cause problems for adults and children.