Ecthyma associated with Moraxella and Staphylococcus epidermidis

Rabionet, Alejandro; Vivar, Karina L.; Mancl, Kimberly; Bennett, Adam E.; Shenefelt, Philip D.

doi:10.1016/j.jdcr.2016.09.017

Cited by 1 publication

(1 citation statement)

References 14 publications

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“…Skin-resident gram-positive bacteria, such as Parvimonas , Micrococcus , Finegoldia , and Anaerococcus , occasionally cause skin infections and chronic wounds ( Murphy and Frick, 2013 , Smith et al., 1999 ). However, gram-negative bacteria, such as Prevotella , Moraxella , and Neisseriaceae , are not frequently found on the skin, but they can rarely cause skin infections ( Mehmood et al., 2014 ; Liu et al., 2015 ; Rabionet et al., 2016 ). Pelomonas , Sarcina , and Caulobacter have not been previously described in skin infections.…”

Section: Discussionmentioning

confidence: 99%

“Alterations in the Skin Microbiota Are Associated With Symptom Severity in Mycosis Fungoides”

Zhang

Seminario‐Vidal

Cohen

et al. 2022

Front. Cell. Infect. Microbiol.

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Cutaneous T cell lymphoma (CTCL), a non-Hodgkin lymphoma, is thought to arise from mature tissue-resident memory T cells. The most common subtypes include Mycosis Fungoides and Sezary Syndrome. The role of skin microbiota remains unclear in the symptom manifestation of MF. Among 39 patients with MF, we analyzed bacteria colonizing MF lesions and non-lesional skin in the contralateral side and characterized regional changes in the skin microbiota related to MF involvement using the difference in relative abundance of each genus between lesional and contralateral non-lesional skin. We investigated the relationship between these skin microbiota alterations and symptom severity. No statistically significant difference was found in bacterial diversity and richness between lesional and non-lesional skin. Different skin microbiota signatures were associated with different symptoms. More pronounced erythema in the lesions was associated with an increase in Staphylococcus. Pain and thick skin in the lesions were associated with a decrease in Propionibacterium. The results of this pilot study suggest that the skin microbiota plays an important role in changing skin phenotypes among patients with MF. Larger skin microbiota studies are needed to confirm these findings and support the use of antibiotic treatment to mitigate CTCL symptoms.

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