1983
DOI: 10.1172/jci110843
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Ecto-5′-Nucleotidase Activity in Human T Cell Subsets. DECREASED NUMBERS OF ECTO-5′-NUCLEOTIDASE POSITIVE CELLS FROM BOTH OKT4+ AND OKT8+ CELLS IN PATIENTS WITH HYPOGAMMAGLOBULINEMIA

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Cited by 36 publications
(2 citation statements)
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“…5NT deficiency has been observed in peripheral blood lymphocytes from patients with hypogammaglobulinemia [41,65] and X-linked congenital agammaglobulinemia [75,76]. However, the 5NT deficiency in these patients is probably a consequence of celt immaturity and not the cause.…”
Section: Ecto-5'-nucleotidase (5nt)mentioning
confidence: 99%
See 1 more Smart Citation
“…5NT deficiency has been observed in peripheral blood lymphocytes from patients with hypogammaglobulinemia [41,65] and X-linked congenital agammaglobulinemia [75,76]. However, the 5NT deficiency in these patients is probably a consequence of celt immaturity and not the cause.…”
Section: Ecto-5'-nucleotidase (5nt)mentioning
confidence: 99%
“…The enzymatic changes during development in the thymus might account for the clonal selection of those T-cells which recognize themselves by preventing the build-up of dATP [50]. Among normal T-cell subpopulations 5NT activity is significantly higher in T suppressor/cytotoxic (OKT8 +) cells than in T-helper/inducer (OKT4 +) cells [52,76].…”
Section: Normal and Neoplastic T-cellsmentioning
confidence: 99%