“…The studies show that life on MCS required major adjustment for both patients and their caregivers, and that the early experience could be frightening and overwhelming. [28][29][30] Despite a new lease on life offered by the treatment, MCS affected multiple aspects of life, including hygiene, sleep, the environment, daily routines, and personal and intimate relationships. 28,31 An initial adjustment period of ≈3 months was difficult for both MCS recipients and informal caregivers.…”