Edge, Fog, and Cloud Against Disease: The Potential of High-Performance Cloud Computing for Pharma Drug Discovery

Bonde, Bhushan

doi:10.1007/978-1-0716-3449-3_8

Cited by 1 publication

(1 citation statement)

References 36 publications

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“…They can simulate the behavior of thousands or even millions of molecules simultaneously to identify those with desirable properties such as high binding affinity to a target protein or low toxicity. This computational approach significantly accelerates the identification of promising drug candidates or vaccine components [64]. For example, scientists leveraged supercomputing capabilities to perform virtual screening of natural compounds against SARS-CoV-2.…”

Section: Drug Discoverymentioning

confidence: 99%

<strong></strong>Supercomputers at the Forefront: From Crisis to Preparedness in Pandemic Response

Mustafa,

Makhawi

2023

Preprint

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The COVID-19 pandemic has unveiled the critical role that supercomputers play in addressing global health crises. This perspective article explores the transformative impact of supercomputing in pandemic response, highlighting how these powerful machines have transitioned from crisis management tools to essential components of preparedness strategies. In this article, we examine the key contributions of supercomputers in combating the pandemic, including their ability to accelerate scientific research, facilitate data analysis, model complex scenarios, and optimize resource allocation. Furthermore, we delve into the role of supercomputing in strengthening public health infrastructure and preparedness. We analyze the lessons learned from the pandemic and emphasize the need for proactive investment in supercomputing capabilities, data infrastructure, and computational expertise as a crucial element of pandemic preparedness efforts. By harnessing the potential of supercomputers, countries can establish robust computational frameworks that enable real-time monitoring, early detection, and effective response to future outbreaks. Moreover, we address the challenges faced by supercomputing initiatives, including the need for enhanced international collaboration, equitable access to computing resources, and the ethical considerations associated with data privacy and security. We discuss potential strategies to overcome these challenges and foster a global network of interconnected supercomputing centers dedicated to pandemic preparedness and response. Finally, we highlight ongoing research and development efforts aimed at advancing supercomputing technologies, such as exascale computing and quantum computing, and their potential to revolutionize pandemic response. We emphasize the importance of sustained investment in research and development to ensure that supercomputing remains at the forefront of future pandemic preparedness strategies.

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Section: Drug Discoverymentioning

confidence: 99%