Editorial: Recent advances in the development of vaccines against Acinetobacter baumannii

Khalili, Saeed; Chen, Wangxue; Jahangiri, Abolfazl

doi:10.3389/fimmu.2023.1187554

Front. Immunol.

2023

DOI: 10.3389/fimmu.2023.1187554

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Editorial: Recent advances in the development of vaccines against Acinetobacter baumannii

Saeed Khalili

Wangxue Chen

Abolfazl Jahangiri

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Host-Pathogen Interactions in Acinetobacter baumannii Infections: Mechanisms of Immune Evasion and Potential Therapeutic Targets

Damilola Wilkie,

Oluwapelumi Alao,

Akin Akinmolayan

2023

Acinetobacter Baumannii - The Rise of a Resistant Pathogen

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The book chapter titled “Host–Pathogen Interactions in Acinetobacter baumannii Infections: Mechanisms of Immune Evasion and Potential Therapeutic Targets” provides an in-depth exploration of the complex interplay between A. baumannii, a notorious multidrug-resistant pathogen, and the host immune system. The chapter will focus on elucidating the mechanisms employed by A. baumannii to evade and subvert the immune response, leading to persistent and challenging infections. It will highlight key aspects of the host immune system, including innate and adaptive immunity, pattern-recognition receptors, and immune cell responses, in the context of A. baumannii infections. Additionally, the chapter discusses the virulence factors and strategies employed by A. baumannii to establish infection, such as biofilm formation and quorum sensing. Importantly, the chapter will explore potential therapeutic targets for combating A. baumannii infections, including novel antimicrobial agents, immunotherapies, and host-directed therapies. The comprehensive analysis of host–pathogen interactions and identification of therapeutic strategies presented in this chapter contribute to our understanding of A. baumannii infections and pave the way for future research directions and healthcare interventions in combating this formidable pathogen.

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Host-Pathogen Interactions in Acinetobacter baumannii Infections: Mechanisms of Immune Evasion and Potential Therapeutic Targets

Damilola Wilkie,

Oluwapelumi Alao,

Akin Akinmolayan

2023

Acinetobacter Baumannii - The Rise of a Resistant Pathogen

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show abstract

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Editorial: Recent advances in the development of vaccines against Acinetobacter baumannii

Cited by 1 publication

References 4 publications

Host-Pathogen Interactions in Acinetobacter baumannii Infections: Mechanisms of Immune Evasion and Potential Therapeutic Targets

Host-Pathogen Interactions in Acinetobacter baumannii Infections: Mechanisms of Immune Evasion and Potential Therapeutic Targets

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