Editorial: Women in multiple sclerosis and other demyelinating disorders: A global perspective

Ciampi, Ethel; Ceccarelli, Andrea; Zuluaga, Maria Isabel

doi:10.3389/fneur.2023.1148659

Cited by 1 publication

(1 citation statement)

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“…MS is more than twice as common in females than in males ( 62 ). Following diagnosis, MS will impact women through all stages of their life, including puberty, family planning, pregnancy and childbearing, breast feeding, infertility treatment, menopause and cancer prevention (e.g., vaccination against papillomavirus, smear tests to detect cervical cancer) ( 63 , 64 ). Several immunologic changes have been reported in post-menopausal women, including decreased CD4 T lymphocytes, B lymphocytes and natural killer cells cytotoxic activity, and increased proinflammatory responses, which all have effects on infection and autoimmunity.…”

Section: Optimising Brain Health In People With Msmentioning

confidence: 99%

MS care: integrating advanced therapies and holistic management

Giovannoni,

Ford,

Schmierer

et al. 2024

Front. Neurol.

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Lifestyle and environmental factors are key determinants in disease causality and progression in neurological conditions, including multiple sclerosis (MS). Lack of exercise, poor diet, tobacco smoking, excessive alcohol intake, social determinants of health, concomitant medications, poor sleep and comorbidities can exacerbate MS pathological processes by impacting brain health and depleting neurological reserves, resulting in more rapid disease worsening. In addition to using disease-modifying therapies to alter the disease course, therapeutic strategies in MS should aim to preserve as much neurological reserve as possible by promoting the adoption of a “brain-healthy” and “metabolically-healthy” lifestyle. Here, we recommend self-regulated lifestyle modifications that have the potential to improve brain health, directly impact on disease progression and improve outcomes in people with MS. We emphasise the importance of self-management and adopting a multidisciplinary, collaborative and person-centred approach to care that encompasses the healthcare team, family members and community support groups.

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Section: Optimising Brain Health In People With Msmentioning

confidence: 99%