“…Interestingly, a new hypothesis can be formulated: the need for cardioprotection of critically ill patients, and one possible mechanism would be through the limitation of heart rate using beta-blockers [10,11], or even sinus node If channel inhibitors (ivabradine) [12]. Studies are needed with more sample volume that can demonstrate the existence of CI in patients who have had an RMD, and analyze the relationship between tachycardiomyopathy and the debut of myocardial dysfunction in critically ill patients.…”