Efeito da idade e sexo sobre a concentração sérica de eritropoietina em equinos da raça Árabe

Abstract

Pesq. Vet. Bras. 32(Supl. The erythropoietin (EPO) is a glicoproteic grow factor synthesized by the adjacent cells in the proximal renal tubes and controlled by feedback mechanism that involve the tension of tissular oxygen. In the presence of low tension of arterial oxygen, the production of EPO increases and it causes a major production of erythrocytes in the marrowbone. Due to poor knowledge of the serum concentration of erythropoietin in equines and the absence of information about the differences between age and gender, the aim of this study was to compare the serum concentration of erythropoietin in Arabian horses, clinically healthy with different age and gender. A total of 31 horses were used from 6 to 12 months old (young) and over 24 months old (adult), 13 males (six young and seven adult) and 18 females (eight young and ten adult) clinically healthy. Blood samples were collected from jugular vein using a vacuntainer with blood clot gel activator and the serum was separated by centrifugation and stored until the time of processing. The EPO serum concentration was measured by radioimmunoassay method (RIA) using a commercial kit (EPO Trac TM 125