Efeito do extrato hidroalcoólico de Aroeira (Schinus terebinthifolius Raddi) na cicatrização de anastomoses colônicas: estudo experimental em ratos

Coutinho, Itágores Hoffman I Lopes Sousa; Torres, Orlando Jorge Martins; Matias, Jorge Eduardo Fouto; Coelho, Júlio Cézar Uili; Júnior, Henrique Jorge Stahlke; Agulham, Miguel Ângelo; Bachle, Enio; Camargo, Paulo Antonio Monteiro; Pimentel, Silvânia Klug; Freitas, Alexandre Coutinho Teixeira de

doi:10.1590/s0102-86502006000900008

Cited by 25 publications

(16 citation statements)

References 12 publications

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“…Actions anti-inflammatory and antiseptic for treatment of wounds, urinary, and respiratory infections are listed as medicinal properties popularly known [19]. Studies showed antimicrobial activity [15, 18, 20–24], antifungal activity [25, 26], as antioxidant [15, 27], and antitumor [18, 28]. Despite its importance, there are a few records about the endophytic community in this plant.…”

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confidence: 99%

Genetic Diversity of Colletotrichum spp. an Endophytic Fungi in a Medicinal Plant, Brazilian Pepper Tree

et al. 2012

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In this study, we reported thirty-nine endophytic fungi identified as Colletotrichum spp. associated with Brazilian pepper tree or aroeira (Schinus terebinthifolius Raddi. Anacardiaceae) in Paraná state, Brazil. These endophytes were identified by morphological and molecular methods, using PCR taxon-specific with CaInt/ITS4, CgInt/ITS4, and Col1/ITS4 primers, which amplify specific bands in C. acutatum, C. gloeosporioides lato sensu, and Colletotrichum boninensis, respectively, and by DNA sequence analysis of the nrDNA internal transcribed spacer region (ITS1, 5.8S, ITS2). We also assayed the presence of dsRNA particles in Colletotrichum spp. isolates. Combining both morphological characters and molecular data, we identified the species C. gloeosporioides, C. boninense, and C. simmondsii. However, we found a high genetic variability intraspecific in C. gloeosporioides which suggests the existence of several other species. Bands of double-stranded RNA (dsRNA) were detected in three of thirty-nine isolates. Identity of these bands was confirmed by RNAse, DNAse, and S1 nuclease treatments for the isolates LGMF633, LGMF726, and LGMF729. This is the first study reporting these particles of dsRNA in C. gloeosporioides.

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Section: Introductionmentioning

confidence: 99%

Genetic Diversity of Colletotrichum spp. an Endophytic Fungi in a Medicinal Plant, Brazilian Pepper Tree

et al. 2012

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“…in a dose of 0.1 g/kg had a positive effect on the healing process of anastomoses of the colon (Coutinho et al, 2006), on healing surgical wounds in the bladder (Lucena et al, 2006) and via percutaneous route, on the back wounds of rats (Castelo-Branco Neto et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Acute and subacute toxicity of Schinus terebinthifolius bark extract

Lima

Vasconcelos

Maranhão

et al. 2009

Journal of Ethnopharmacology

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“…Furthermore, studies on the composition of plant parts, isolated compounds such as: essential oils, flavonoids, fractions enriched of flavonoids, Shinol (flavonoid) and masticadienoic acid, biflavonoids isolated and triterpenes. Have been studied the morphology and anatomy of the seed, barks and leaves, chemical and microscopic examination of the plant, barks development and fruits development, even clinical drug trials (phase I) of an herbal compound (Schinus, Plectranthus and Eucalyptus) 1,3,4,5,7,8,9,10,11,15,18,19,20,21,23,25,26,28,30,31,32,33,34 .…”

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Schinus terebinthifolius raddi (anacardiaceae) no processo de cicatrização de gastrorrafias em ratos

Santos

Barros

Malafaia

et al. 2012

ABCD, arq. bras. cir. dig.

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-Background -Gastrorraphy, isolated or associated with the use of biological adhesives, was throughout the history of surgery the usual way to promote healing in gastric lesions and the use of herbal medicine has been increasingly more employed. Aim -To evaluate the wound healing in the stomach of rats with the use of the hydroalcoholic extract of Schinus terebinthifolius Raddi (aroeira). Methods -Sixty rats, adult males, were divided into two groups: aroeira group and control group. Each one was subdivided into four subgroups of 15 animals (test groups). Each subdivided subgroup was also subdivided into three subgroups of five rats (deaths periods of 7, 14 and 21 days). All animals underwent the same surgical procedure (injury and stomach suture); animals in the aroeira group received daily dose of 100 mg/kg of hydroalcoholic extract via gavage while the control group received isotonic saline solution. Parameters evaluated were: macroscopic and microscopic changes, test for resistance to insufflation of atmospheric air and test for tensile strength. Results -All animals had good healing of the abdominal wall and gastrorraphies without infection and dehiscence. Both groups had adhesions to the gastrorraphies surfaces with neighboring organs. The resistance test by insufflation of atmospheric air and tensile strength showed higher average of pressure on the 7th day and breaking strength in the time periods for the aroeira group. The intensity of chronic inflammation revealed statistically significant differences in the variables fibroblast proliferation and collagen. Conclusion -The use of hydroalcoholic extract of Schinus terebinthifolius Raddi accelerated the stomach healing in rats ABCDDV/862 RESUMO -Racional -A gastrorrafia isolada ou associada ao uso de adesivos biológicos constituiu ao longo da história da cirurgia a forma usual de promover a cicatrização nas lesões gástricas e o uso de fitoterápicos tem sido cada vez mais empregado. Objetivo -Avaliar a cicatrização de ferida provocada no estômago de ratos com uso do extrato hidroalcoólico de Schinus terebinthifolius Raddi. Métodos -Foram utilizados 60 ratos, adultos, machos, distribuídos em dois grupos: grupo aroeira e grupo controle, os quais foram subdivididos em três subgrupos de cinco animais conforme o momento das mortes dos animais (7, 14 e 21 dias). Todos os animais foram submetidos ao mesmo procedimento cirúrgico (lesão e rafia do estômago) diferindo apenas que os animais do grupo aroeira receberam dose diária de 100 mg/kg do extrato hidroalcoólico via gavagem enquanto o grupo controle recebeu solução salina isotônica. Os parâmetros avaliados foram: alterações macroscópicas e microscópicas, teste de resistência à insuflação de ar atmosférico e teste pela força de tração. Resultados -Todos os animais demonstraram boa cicatrização da parede abdominal e das gastrorrafias, sem infecção e deiscência. Ambos os grupos apresentaram aderências à superfície das gastrorrafias com órgãos vizinhos. O teste de resistência por insuflação de ar atmosféric...

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Efeito do extrato hidroalcoólico de Aroeira (Schinus terebinthifolius Raddi) na cicatrização de anastomoses colônicas: estudo experimental em ratos

Cited by 25 publications

References 12 publications

Genetic Diversity of Colletotrichum spp. an Endophytic Fungi in a Medicinal Plant, Brazilian Pepper Tree

Genetic Diversity of Colletotrichum spp. an Endophytic Fungi in a Medicinal Plant, Brazilian Pepper Tree

Acute and subacute toxicity of Schinus terebinthifolius bark extract

Schinus terebinthifolius raddi (anacardiaceae) no processo de cicatrização de gastrorrafias em ratos

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