Efeitos da insuflação de dióxido de carbono sobre a oxigenação cerebral regional durante cirurgia laparoscópica em crianças: um estudo prospectivo

Tuna, Ayça Taş; Akkoyun, İbrahim; Darçın, Sevtap; Palabıyık, Onur

doi:10.1016/j.bjan.2014.10.006

Cited by 14 publications

(2 citation statements)

References 9 publications

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“…Westgarth-Taylor et al ( 21 ) found an increase in cerebral oxygenation after insufflation in paediatric patients who had undergone laparoscopic surgery. In the other two studies, they found no change in cerebral oxygenation due to pneumoperitoneum compared to the open technique ( 22 , 23 ). Tsypin et al ( 24 ) reported an average reduction of 3% in regional cerebral tissue saturation in children during gynaecological laparoscopic interventions.…”

Section: Discussionmentioning

confidence: 88%

Effects of Pneumoperitoneum on Splanchnic Oxygenation during Abdominal Laparoscopic Surgery in Paediatric Patients: A prospective, Observational Study

Kılınç¹,

Türk²,

Sayin³

et al. 2021

Turk J Anaesthesiol Reanim

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Objective Pneumoperitoneum can cause disruption in splanchnic perfusion. This study aims to investigate effects of pneumoperitoneum on splanchnic oxygenation during abdominal laparoscopic surgery in paediatric patients with NIRS (Near-Infrared Spectroscopy). Material and methods A total of 45 patients between 1 and 4 years of age with ASA physical status I–II and scheduled to undergo abdominal laparoscopic surgery under general anaesthesia were enrolled in this prospective, observational surgery. No premedication was used. Standard monitoring and regional splanchnic saturation (rSPcO 2 ), regional cerebral oxygen saturation (rScO 2 ) with NIRS were established before anaesthesia. Anaesthesia was induced with an inhalational agent and maintained with an oxygen/air mixture and sevoflurane. Peripheral oxygen saturation (SPO 2 ), rSPcO 2 , rScO 2 , heart rate (HR), mean arterial pressure (MAP), end tidal CO 2 (Et-CO 2 ), and insufflation pressure (IP) were continuously monitored during administration of anaesthesia and recorded. After intubation (baseline T0); before CO 2 insufflation induced pneumoperitoneum (PP) (T1); CO 2 PP insufflation (T2); 5 minutes after PP insufflation (T3); 10 minutes after PP insufflation (T4); 15 minutes after PP insufflation (T5); 20 minutes after PP insufflation (T6); 30 minutes after PP insufflation (T7), 60 minutes after PP insufflation (T8), and after desufflation (T9). Bradycardia and hypotension were recorded. Paracetamol IV 10 mg kg −1 was applied for post-operative analgesia. p<0.05 wasconsidered significant. Results HR, rScO 2 , and rSPcO 2 decreased at all measured time intervals when compared to T0 (p<0.01) MAP decreased at T1 compared to T0 (p<0.001). Et-CO 2 increased at T3-T4-T5-T6 compared to T0 (p<0.001). Conclusion We found that pneumoperitoneum reduced splanchnic oxygenation during laparoscopic abdominal surgery in paediatric patients, which was measured using NIRS.

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Section: Discussionmentioning

confidence: 88%

Effects of Pneumoperitoneum on Splanchnic Oxygenation during Abdominal Laparoscopic Surgery in Paediatric Patients: A prospective, Observational Study

Kılınç¹,

Türk²,

Sayin³

et al. 2021

Turk J Anaesthesiol Reanim

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“…Subtotal gastrectomy is a major operation for gastric cancer, the operative time is long and is further extended by waiting for pathological results and dissecting local lymph nodes. When the long operative time under general anesthesia causes hypoventilation or other respiratory system complications, the gas exchange capacity is impaired and desaturation rSO 2 often results, which may be significantly correlated with neurological complications, cognitive function, and prolonged length of stay (6,7). Therefore, it is important to detect early diagnosis indicators and serological markers of POCD so that it can be prevented after subtotal gastrectomy.…”

Section: Introductionmentioning

confidence: 99%

Effect of general anesthesia on serum β-amyloid protein and regional cerebral oxygen saturation of elderly patients after subtotal gastrectomy

Pan¹,

Wang²,

Mu³

et al. 2016

Experimental and Therapeutic Medicine

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The aim of the present study was to investigate the influence of general anesthesia on serum β-amyloid protein (Aβ) and regional cerebral oxygen saturation (rSO2) of elderly patients after subtotal gastrectomy. From June, 2014 to December, 2015, among 168 patients undergoing subtotal gastrectomy, the Mini-Mental State Examination and Montreal Cognitive Assessment was administered the day prior to surgery and the second and ninth days after the operation. In addition, we administered the tests to 168 healthy adult volunteers (healthy controls) who were treated in our hospital medical center in the same period. Near-infrared spectroscopy technology was used for continuous monitoring of the intraoperative rSO2, and the mean of intraoperative rSO2 was then calculated. Of the 168 patients, 28 developed postoperative cognitive dysfunction (POCD) and the remaining 140 patients were normal (control). The ELISA method was used to test the expression levels of serum Aβ in the three groups and statistical analyses were conducted. Serum Aβ level in the POCD group was significantly higher than that in the control and healthy control groups, and the difference was statistically significant (P<0.05). The rSO2 level in the patients with POCD was significantly lower than the control group (P<0.05). The correlation analysis with Aβ as an independent variable and other factors as dependent variables revealed that the serum Aβ level negatively correlated with rSO2 (r=−1.6749, P<0.05). The combined Aβ and rSO2 may be useful for the diagnosis and prevention of POCD after subtotal gastrectomy under general anesthesia.

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Minimally Invasive Versus Open Surgical Approaches in Children: Pros/Cons

Rim

Verghese

Kane

2021

Anesthetic Management in Pediatric General Surgery

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Efeitos da insuflação de dióxido de carbono sobre a oxigenação cerebral regional durante cirurgia laparoscópica em crianças: um estudo prospectivo

Abstract: Carbon dioxide insufflation during pneumoperitoneum in pediatric patients may not affect cerebral oxygenation under laparoscopic surgery.

Cited by 14 publications

References 9 publications

Effects of Pneumoperitoneum on Splanchnic Oxygenation during Abdominal Laparoscopic Surgery in Paediatric Patients: A prospective, Observational Study

Effects of Pneumoperitoneum on Splanchnic Oxygenation during Abdominal Laparoscopic Surgery in Paediatric Patients: A prospective, Observational Study

Effect of general anesthesia on serum β-amyloid protein and regional cerebral oxygen saturation of elderly patients after subtotal gastrectomy

Minimally Invasive Versus Open Surgical Approaches in Children: Pros/Cons

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