Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review

Strydonck, D.A.C. Van; Slot, Dagmar Else; Velden, U. van der; Weijden, F. van der

doi:10.1111/j.1600-051x.2012.01883.x

Cited by 285 publications

(261 citation statements)

References 85 publications

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“…Other common side effects are increased calculus formation and change in taste sensation (19). Burning sensation, hypersensitivity, mucosal lesions, and numbness have been reported less frequently (19). Because of these important side effects of CHX, patients prefer herbal mouthwash solutions, which are effective in preventing and treating gingivitis without side effects.…”

Section: Discussionmentioning

confidence: 99%

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Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

Góes

Dutra

Lisboa

et al. 2016

Journal of Oral Science

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Section: Discussionmentioning

confidence: 99%

“…The most common side effect of long-term CHX rinse use is an extrinsic brown staining of the teeth and tongue (3). Other common side effects are increased calculus formation and change in taste sensation (19). Burning sensation, hypersensitivity, mucosal lesions, and numbness have been reported less frequently (19).…”

Section: Discussionmentioning

confidence: 99%

Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

Góes

Dutra

Lisboa

et al. 2016

Journal of Oral Science

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“…Thus, it is well established that chlorhexidine gluconate solution is an effect gargling agent that can be used after a surgical operation for periodontal disease [55][56][57][58][59][60][61][62][63] . However, the international standard guidelines recommend the use of a solution with a high concentration of 0.12-0.2 % in the USA and Europe, whereas a diluted solution of less than 0.05 % is used in Japan.…”

Section: Group Dm+chlomentioning

confidence: 99%

The Effect of Insulin Administration and Antibacterial Irrigation with Chlorhexidine Gluconate on the Disturbance of Periodontal Tissue Caused by Food Impaction in Streptozotocin-Induced Diabetic Rats

Nakamura

Sakagami

Ozaki

et al. 2015

J. Hard Tissue Biology.

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Abstract:This histopathological study used streptozotocin (STZ)-induced diabetic rats to investigate insulin administration in conjunction with an antibacterial irrigation of chlorhexidine gluconate solution and its effect on the disturbance of periodontal tissue and destruction of alveolar bone induced by mechanical compression at the col due to food impaction. The experimental animals were divided into normal rats (Group N) and STZinduced diabetes mellitus (DM) rats. Mechanical compression was done by insertion of a gutta-percha point (GP). The diabetic rats were further divided into Group (DM+Ins), in which insulin was administered, and into Group (DM+Chlo), in which 0.2% chlorhexidine gluconate solution was used for bactericidal irrigation. Histological comparisons of the destructive process and reparative changes of the periodontal tissue were performed at 1, 3, 7 and 14 days after the col compression. The antibacterial irrigation effects caused by chlorhexidine gluconate solution were considered to be low during the early stages. However, since there was no sequestrum formation at the alveolar crest at 7 days after the col compression, reparative changes of periodontal tissue were able to progress. These results suggest that there was a constant antibacterial effect after the chlorhexidine gluconate solution irrigation. Even so, the use of only chlorhexidine gluconate solution in cases with very destructive changes or in cases with persistent mechanical compression, made it difficult to perform a successful treatment of the disturbance of the periodontal tissue. Results for Group (DM+Ins) were better than those for Group (DM+Chlo) with regard to the inhibition of bacterial contaminant at the food impaction area, alleviation, and improvement of the healing process after disturbance in the periodontal tissue. The persistent use of 0.2 % chlorhexidine gluconate solution did appear to lead to a constant effect on the bacteria. Therefore, when treating a disturbance of the periodontal tissue due to food impaction in the diabetic state, the first step should include the administration of insulin in order to improve the diabetic state.

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“…8 However, the recommendation of daily use of CHX is hindered by adverse effects associated with this antiseptic. 9 Several other antiseptics have been suggested in the literature. 10,11,12 Among them, triclosan (TCS) can be found in different formulations of dentifrices and rinsing solutions.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of a triclosan formula in controlling early subgingival biofilm formation: a randomized trial

et al. 2015

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The aim of this study was to determine the efficacy of rinses with slurries of a dentifrice containing triclosan (TCS), as compared with rinses with slurries from a control dentifrice, in controlling early subgingival biofilm formation. A double-blind, randomized and cross-over clinical trial was designed, and 26 dental students were included. In the first period, participants were randomized to rinse with a TCS slurry or a control slurry, in a 12 h interval, and to refrain from mechanical cleaning. A Plaque Free Zone Index was assessed at 24 h, 48 h, 72 h and 96 h. After a washout period of 10 days, the second experimental period was conducted, following the same protocol as the first period, except that the slurry groups were switched. Use of the TCS slurry resulted in a significantly higher percentage of plaque-free surfaces, both at 24 h and at 72 h (p < 0.01). In the of 48-72 h interval, the triclosan slurry showed a lower percentage of sites converted to a score of 2 (38.1% for the test versus 40% for the control product, p = 0.015).In conclusion, rinsing with slurries of dentifrice containing TCS retards the down growth of bacterial biofilms from the supra-to the subgingival environment.

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Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review

Abstract: In gingivitis patients, CHX mouthrinses together with OH versus placebo- or control mouthrinse provide significant reductions in plaque and gingivitis scores, but a significant increase in staining score.

Cited by 285 publications

References 85 publications

Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

The Effect of Insulin Administration and Antibacterial Irrigation with Chlorhexidine Gluconate on the Disturbance of Periodontal Tissue Caused by Food Impaction in Streptozotocin-Induced Diabetic Rats

Efficacy of a triclosan formula in controlling early subgingival biofilm formation: a randomized trial

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