Effect of a Self-Etch Adhesive Containing Nanobioglass on Postoperative Sensitivity of Posterior Composite Restorations - A Randomized Trial

Abstract

BACKGROUND: Postoperative sensitivity is one of the major problems regarding posterior resin composite restorations that causes patient discomfort, maybe a reason for replacement of the restoration with an additional office time.
 AIM: To evaluate the effect of the addition of a Nanobioglass to a self-etch adhesive on the reduction of post-operative sensitivity following composite restorations versus a self-etch adhesive that is free of Nanobioglass agent.
 MATERIALS AND METHODS: Sixteen patients having class II carious lesions were included in the study. After cavity preparation, each tooth was randomised to one of the following restorative treatments. Teeth in the control group were restored using self-etch adhesive (OptiBond All-In-One, Kerr) that is free of nanobioglass agent, and nano-hybrid resin composite (Herculite Ultra, Kerr). Restoration of teeth in the experimental group was similar to the control except that a nanobioglass agent was added to the self-etch adhesive. Patients were contacted for evaluation of postoperative sensitivity at 1 day, 1 week, 1 month, and 3 months. Data were analyzed using friedmann test followed by fisher exact test.
 RESULTS: The experimental group (self-etch adhesive containing nanobioglass) showed a significantly less postoperative sensitivity compared with the control group (Self-etch adhesive free of nanobioglass) at 1 day, and 1-week evaluation periods. While both groups did not possess any significant difference at 1 month, and 3 months periods.
 CONCLUSION: The problem of postoperative sensitivity following resin composite restorations could be solved by the addition of bioglass nanoparticles into dental adhesives.

Total Etch versus Self Etch Adhesive; Effect on Post-Operative Sensitivity

“…2 Some studies showed no significant difference in post-operative sensitivity either by using total etch adhesives or by self-etch adhesives. 11 Oliveira in his one month recall period concluded that self-etch causes mild post-operative sensitivity in deep Class-I cavities that reduce with the period of time 10 which is in accordance with present study. Krithikadatta et al conducted meta-analysis and concluded no significant difference in Post-operative sensitivity with both total etch and self etch.…”

“…As self-etch adhesives do not completely remove the smear layer, many practitioners believe that self-etch adhesives cause less post-operative sensitivity than total etch adhesives. 11 Applying etchant in deep cavity as a component of the etch and rinse approach removed the smear layer and increased the permeability of dentin make the tooth vulnerable to postoperative sensitivity if dentinal tubules were not occluded by hybridization. 12 Amin et al conducted a similar study over a period of one week and concluded post-operative sensitivity with both self-etch adhesive and total etch adhesive remains till one week.…”

Clinical Efficacy of a Novel Titania Nanoparticle-Reinforced Bonding Agent in Reducing Post-Restorative Sensitivity: A randomized clinical trial

“…Test value for population mean was 1.38, while predicted population mean was 3.69, and population standard deviation was 1.6. 8 Consecutive non-probability sampling method was utilised in this trial. Participants satisfying inclusion criteria were filtered from Outpatient department and were randomly distributed by Trial-autonomous researcher in each interventional group.…”

“…However, this attribute of bonding agent is subjected to time-dependent decline, mainly due to the longterm instability and deterioration of hybrid layer. 7,8 By fortifying bonding agents with nanoparticles, significant enhancements in physiochemical attributes and long-term stability of dentin-adhesive interface can be achieved. 9 The rationale of this study was to upgrade the mechanical atributes of bonding agent by the addition of titania nanoparticles to reduce the issues of sensitivity associated with composite restorations.…”

“…However, this attribute of bonding agent is subjected to time-dependent decline, mainly due to the long-term instability and deterioration of hybrid layer. 7 , 8 …”